Risk factors for nosocomial nontraumatic coma: sepsis and respiratory failure

Coma's are a major cause of clinical deterioration or death. Identification of risks that predispose to coma are important in managing patients; however, the risk factors for nosocomial nontraumatic coma (NNC) are not well known. Our aim was to investigate the risk factors in patients with NNC....

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Bibliographic Details
Published in:Journal of multidisciplinary healthcare 2016-01, Vol.9 (1), p.463-468
Main Authors: Zhou, Ye-Ting, Wang, Shao-Dan, Wang, Guang-Sheng, Chen, Xiao-Dong, Tong, Dao-Ming
Format: Article
Language:English
Subjects:
Acute respiratory failure
Blood pressure
Clinical deterioration
Coma
Consciousness
GCS
Heart rate
Hospitals
Infection
Infections
Intensive care
Medical research
Medicine, Experimental
Nosocomial infection
Nosocomial nontraumatic coma
Original Research
Pathogenesis
Pneumonia
Respiratory failure
Risk factors
Sepsis
Ventilators
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Summary:Coma's are a major cause of clinical deterioration or death. Identification of risks that predispose to coma are important in managing patients; however, the risk factors for nosocomial nontraumatic coma (NNC) are not well known. Our aim was to investigate the risk factors in patients with NNC. A retrospective case-control design was used to compare patients with NNC and a control group of patients without coma in a population-based cohort of 263 participants from the neurological intensive care unit in Shuyang County People's Hospital of Northern China. Coma was diagnosed by a Glasgow Coma Scale score ≤8. Adjusted odds ratios for patients with NNC were derived from multivariate logistic regression analyses. A total of 96 subjects had NNC. The prevalence of NNC was 36.5% among the subjects. Among these, 82% had acute cerebrovascular etiology. Most of the NNC usually occurred at day 3 after admission to the neurological intensive care unit. Patients with NNC had higher hospital mortality rates (67.7% vs 3%,
ISSN:1178-2390
1178-2390
DOI:10.2147/JMDH.S113682