Urinary sodium potassium ratio is associated with clinical success after adrenalectomy in patients with unilateral primary aldosteronism

Background: The urinary sodium potassium (NaK) ratio is associated with dietary sodium and potassium intake and blood pressure, and it also reflects the activity of aldosterone. Herein we evaluated the value of the urinary NaK ratio in predicting the surgical outcomes of patients with unilateral pri...

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Bibliographic Details
Published in:Therapeutic advances in chronic disease 2021, Vol.12, p.2040622321990274-2040622321990274
Main Authors: Lee, Ming-Jse, Sun, Chiao-Yin, Lu, Ching-Chu, Chang, Yuan-Shian, Pan, Heng-Chih, Lin, Yen-Hung, Wu, Vin-Cent, Chueh, Jeff S.
Format: Article
Language:English
Subjects:
Adrenal glands
Blood pressure
Endocrine disorders
Endocrine system
Gastrointestinal surgery
Original Research
Potassium
Sodium
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Summary:Background: The urinary sodium potassium (NaK) ratio is associated with dietary sodium and potassium intake and blood pressure, and it also reflects the activity of aldosterone. Herein we evaluated the value of the urinary NaK ratio in predicting the surgical outcomes of patients with unilateral primary aldosteronism (uPA). Methods: This non-concurrent prospective cohort study was conducted from 2011 to 2017 and included 241 uPA patients who had undergone adrenalectomy. Predictors of successful clinical outcomes were analyzed using logistic regression. Results: Among the 241 uPA patients, 197 (81.7%) achieved clinical complete or partial success. A urinary sodium potassium ratio
ISSN:2040-6223
2040-6231
DOI:10.1177/2040622321990274