Higher incidence of metabolic syndrome components in vitiligo patients: a prospective cross-sectional study

• Published in: Anais brasileiros de dermatología 2020-03, Vol.95 (2), p.165-172
• Main Authors: Tanacan, Efsun, Atakan, Nilgun
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Cross-Sectional Studies; DERMATOLOGY; Female; Humans; Incidence; Investigation; Male; Metabolic syndrome; Metabolic Syndrome - blood; Metabolic Syndrome - complications; Metabolic Syndrome - epidemiology; Middle Aged; Obesity; Prospective Studies; Reference Values; Risk Factors; Severity of Illness Index; Sex Distribution; Statistics, Nonparametric; Turkey - epidemiology; Vitamin B 12 Deficiency - blood; Vitiligo; Vitiligo - blood; Vitiligo - complications; Vitiligo - epidemiology; Young Adult
• ISSN: 0365-0596; 1806-4841; 1806-4841
• DOI: 10.1016/j.abd.2019.07.006

To investigate the association between vitiligo and metabolic syndrome. A prospective cross-sectional study was conducted between 2014 and 2016. Study (n=155) and control groups (n=155) were evaluated for metabolic syndrome according to National Cholesterol Education Program Adult Treatment Panel III and the International Diabetes Federation criteria. Study group was divided into three groups according to their vitiligo area severity index and vitiligo disease activity score values (Group 1: 6.89 for VASI score, Group A: −1–0, Group B: 1–2 and Group C: 3–4 for vitiligo disease activity score respectively). MetS rates according to both criteria were compared between the vitiligo disease activity score and vitiligo area severity index groups. Metabolic syndrome rates were 37.4% and 40% in the study group and 19.4% and 26.5% in the control group according to National CholesterolEducation Program Adult Treatment Panel III and International Diabetes Federation criteria, respectively (p