Partial molecular characterization of Sm8, a tegumental antigen of Schistosoma mansoni

Sm8 is a major tegumental antigen of Schistosoma mansoni. The partial cDNA was isolated and analyzed. Sequence analysis revealed transmembrane compatible hydrophobic domains and a putative leucine zipper pattern. The mRNA and the protein are predominantly expressed in adult worms.

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Bibliographic Details
Published in:Memórias do Instituto Oswaldo Cruz 2002-01, Vol.97 Suppl 1 (suppl 1), p.91-93
Main Authors: Abath, Frederico G C, Xavier, Edeneide M, Montenegro, Sílvia M L, Werkhauser, Roberto P
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Antigens, Helminth - analysis
Antigens, Helminth - genetics
Base Sequence
Blotting, Western
Calcium-Binding Proteins - chemistry
Calcium-Binding Proteins - genetics
characterization
DNA, Complementary - analysis
Helminth Proteins - chemistry
Helminth Proteins - genetics
Molecular Sequence Data
PARASITOLOGY
Schistosoma mansoni
Schistosoma mansoni - immunology
tegumental antigen
TROPICAL MEDICINE
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Description
Summary:Sm8 is a major tegumental antigen of Schistosoma mansoni. The partial cDNA was isolated and analyzed. Sequence analysis revealed transmembrane compatible hydrophobic domains and a putative leucine zipper pattern. The mRNA and the protein are predominantly expressed in adult worms.
ISSN:0074-0276
1678-8060
0074-0276
1678-8060
DOI:10.1590/S0074-02762002000900018