Clinical valuables related to resolution of complete or advanced atrioventricular block after steroid therapy in patients with cardiac sarcoidosis

Background Prediction of atrioventricular block (AVB) resolution after steroid therapy in patients with cardiac sarcoidosis (CS) is difficult. Methods We identified 24 patients with CS and complete or advanced AVB receiving steroid therapy. AVB resolution was assessed by reviewing surface electrocar...

Full description

Saved in:
Bibliographic Details
Published in:Journal of arrhythmia 2021-08, Vol.37 (4), p.1093-1100
Main Authors: Nabeta, Takeru, Hara, Masahiko, Naruke, Takashi, Maemura, Kenji, Oki, Takumi, Yazaki, Mayu, Fujita, Teppei, Ikeda, Yuki, Ishii, Shunsuke, Koitabashi, Toshimi, Ako, Junya
Format: Article
Language:English
Subjects:
atrioventricular block
Cardiac patients
cardiac sarcoidosis
Care and treatment
Ejection fraction
Electrocardiogram
Electrocardiography
Enzymes
Heart
Heart block
immunosuppression therapy
inflammation
Laboratories
Lysozyme
Magnetic resonance imaging
Original
Pacemakers
Questioning
Sarcoidosis
Scintigraphy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Prediction of atrioventricular block (AVB) resolution after steroid therapy in patients with cardiac sarcoidosis (CS) is difficult. Methods We identified 24 patients with CS and complete or advanced AVB receiving steroid therapy. AVB resolution was assessed by reviewing surface electrocardiogram and the percentage of ventricular pacing required on subsequent device interrogation reports. Results AVB resolution was noted in eight (33%) patients 1 year after receiving steroid therapy. Univariate Cox regression analysis demonstrated that left ventricular ejection fraction (LVEF) (hazard ratio [HR] 1.07, 95% confidence interval [CI] 1.01‐1.14, P = .016), interval from recognized AVB to start of steroid therapy (HR 0.98, 95% CI 0.95‐0.99, P 
ISSN:1880-4276
1883-2148
DOI:10.1002/joa3.12583