Globalization of a telepathology network with artificial intelligence applications in Colombia: The GLORIA program study protocol

• Published in: Journal of pathology informatics 2024-12, Vol.15, p.100394, Article 100394
• Main Authors: Mosquera-Zamudio, Andrés, Gomez-Suarez, Marcela, Sprockel, John, Riaño-Moreno, Julian Camilo, Janssen, Emiel A.M., Pantanowitz, Liron, Parra-Medina, Rafael
• Format: Article
• Language: English
• Subjects: 0000; 1111; Cancer; Computational pathology; Digital pathology; Telemedicine; Telepathology
• ISSN: 2153-3539; 2229-5089; 2153-3539
• DOI: 10.1016/j.jpi.2024.100394

In Colombia, cancer is recognized as a high-cost pathology by the national government and the Colombian High-Cost Disease Fund. As of 2020, the situation is most critical for adult cancer patients, particularly those under public healthcare and residing in remote regions of the country. The highest lag time for a diagnosis was observed for cervical cancer (79.13 days), followed by prostate (77.30 days), and breast cancer (70.25 days). Timely and accurate histopathological reporting plays a vital role in the diagnosis of cancer. In recent years, digital pathology has been globally implemented as a technological tool in two main areas: telepathology (TP) and computational pathology. TP has been shown to improve rapid and timely diagnosis in anatomic pathology by facilitating interaction between general laboratories and specialized pathologists worldwide through information and telecommunication technologies. Computational pathology provides diagnostic and prognostic assistance based on histopathological patterns, molecular, and clinical information, aiding pathologists in making more accurate diagnoses. We present the study protocol of the GLORIA digital pathology network, a pioneering initiative, and national grant-approved program aiming to design and pilot a Colombian digital pathology transformation focused on TP and computational pathology, in response to the general needs of pathology laboratories for diagnosing complex malignant tumors. The study protocol describes the design of a TP network to expand oncopathology services across all Colombian regions. It also describes an artificial intelligence proposal for lung cancer, one of Colombia's most prevalent cancers, and a freely accessible national histopathological image database to facilitate image analysis studies. National Digital Pathology network including Whole Slide Imaging Telepathology System and database for Artificial Intelligence (AI) models. SDC: Satellite Digitization Center COE: Center of excellence. [Display omitted] •The GLORIA program marks a significant milestone in Latin American Digital Pathology.•GLORIA integrates public and private healthcare systems to address pathologist shortage.•The performance evaluation will be through a novel qualitative and quantitative method study.