Global Burden of Lumpy Skin Disease, Outbreaks, and Future Challenges

Lumpy skin disease (LSD), a current global concern, causes economic devastation in livestock industries, with cattle and water buffalo reported to have higher morbidity and lower mortality rates. LSD is caused by lumpy skin disease virus (LSDV), a member of the Poxviridae family. It is an enzootic,...

Full description

Saved in:
Bibliographic Details
Published in:Viruses 2023-08, Vol.15 (9), p.1861
Main Authors: Akther, Mahfuza, Akter, Syeda Hasina, Sarker, Subir, Aleri, Joshua W, Annandale, Henry, Abraham, Sam, Uddin, Jasim M
Format: Article
Language:English
Subjects:
Africa, Northern
Animal diseases
Animals
Asia - epidemiology
Bovidae
Buffaloes
Cattle
Diagnosis
Disease Outbreaks
Distribution
Domestication
economic impact
Epidemics
Genes
Genomes
global biosecurity challenges
Health aspects
historical outbreak
Humans
Infections
Livestock
Lumpy skin disease
Lumpy Skin Disease - epidemiology
Lumpy Skin Disease - prevention & control
Medical research
Milk production
Morbidity
Mutation
Outbreaks
Pathogens
Review
Sheep
Skin diseases
vaccination
Vaccine development
Vaccines
Viral infections
Virulence
Viruses
Zambia
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Lumpy skin disease (LSD), a current global concern, causes economic devastation in livestock industries, with cattle and water buffalo reported to have higher morbidity and lower mortality rates. LSD is caused by lumpy skin disease virus (LSDV), a member of the Poxviridae family. It is an enzootic, rapidly explorative and sometimes fatal infection, characterized by multiple raised nodules on the skin of infected animals. It was first reported in Zambia in 1929 and is considered endemic in Africa south of the Sahara desert. It has gradually spread beyond Africa into the Middle East, with periodic occurrences in Asian and East European countries. Recently, it has been spreading in most Asian countries including far East Asia and threatens incursion to LSD-free countries. Rapid and accurate diagnostic capabilities, virus identification, vaccine development, vector control, regional and international collaborations and effective biosecurity policies are important for the control, prevention, and eradication of LSD infections. This review critically evaluates the global burden of LSD, the chronological historical outbreaks of LSD, and future directions for collaborative global actions.
ISSN:1999-4915
1999-4915
DOI:10.3390/v15091861