Detection of carbon dioxide embolism by transesophageal echocardiography during transanal/perineal endoscopic surgery: a pilot study

• Published in: Scientific reports 2022-11, Vol.12 (1), p.20487-5, Article 20487
• Main Authors: Matsumoto, Yoshiko, Hasegawa, Suguru, Ohno, Ryo, Kajitani, Ryuji, Munechika, Taro, Nagano, Hideki, Komono, Akira, Aisu, Naoya, Yoshimatsu, Gumpei, Yoshida, Yoichiro, Murayama, Kazuya, Shigematsu, Kenji, Akiyoshi, Kozaburo
• Format: Article
• Language: English
• Subjects: 692/4019/592; 692/4020; Anesthesia; Anorectal; Blood pressure; Carbon dioxide; Carbon Dioxide - adverse effects; Echocardiography; Echocardiography, Transesophageal - adverse effects; Embolism; Embolisms; Endoscopy; Heart; Humanities and Social Sciences; Humans; Insufflation - adverse effects; Male; multidisciplinary; Patients; Perineum; Pilot Projects; Prostate; Science; Science (multidisciplinary); Surgery; Ventricle
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-24888-x

The transanal/perineal (ta/tp) endoscopic approach has been widely used for anorectal surgery in recent years, but carbon dioxide embolism is a possible lethal complication. The frequency of this complication in this approach is not known. In this study, we investigated the frequency of intraoperative (including occult) carbon dioxide embolism using transesophageal echocardiography. Patients who underwent surgery via the ta/tp approach and consented to participate were included. Intraoperative transesophageal echocardiography was used to observe the right ventricular system in a four-chamber view. Changes in end-tidal carbon dioxide (EtCO 2 ), oxygen saturation (SpO 2 ), and blood pressure were taken from anesthesia records. Median maximum insufflation pressure during the ta/tp approach was 13.5 (12–18) mmHg. One patient (4.8%) was observed to have a bubble in the right atrium on intraoperative transesophageal echocardiography, with a decrease in EtCO 2 from 39 to 35 mmHg but no obvious change in SpO 2 or blood pressure. By lowering the insufflation pressure from 15 to 10 mmHg and controlling bleeding from the veins around the prostate, the gas rapidly disappeared and the operation could be continued. Among all patients, the range of variation in intraoperative EtCO 2 was 5–22 mmHg, and an intraoperative decrease in EtCO 2 of > 3 mmHg within 5 min was observed in 19 patients (median 5 mmHg in 1–10 times).Clinicians should be aware of carbon dioxide embolism as a rare but potentially lethal complication of anorectal surgery, especially when using the ta/tp approach.