Biomimetic caged platinum catalyst for hydrosilylation reaction with high site selectivity

Natural enzymes exhibit unparalleled selectivity due to the microenvironment around the active sites, but how to design artificial catalysts to achieve similar performance is a formidable challenge for the catalysis community. Herein, we report that a less selective platinum catalyst becomes highly...

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Bibliographic Details
Published in:Nature communications 2021-01, Vol.12 (1), p.64-64, Article 64
Main Authors: Pan, Ganghuo, Hu, Chunhua, Hong, Song, Li, Huaping, Yu, Dongdong, Cui, Chengqian, Li, Qiaosheng, Liang, Nianjie, Jiang, Ying, Zheng, Lirong, Jiang, Lei, Liu, Yuzhou
Format: Article
Language:English
Subjects:
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Biomimetics
Cages
Catalysis
Catalysts
Design
Enzymatic activity
Enzyme activity
Enzymes
Functional groups
Humanities and Social Sciences
Hydrosilylation
Ligands
Microenvironments
multidisciplinary
Platinum
Reaction kinetics
Science
Science (multidisciplinary)
Selectivity
Substrates
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Summary:Natural enzymes exhibit unparalleled selectivity due to the microenvironment around the active sites, but how to design artificial catalysts to achieve similar performance is a formidable challenge for the catalysis community. Herein, we report that a less selective platinum catalyst becomes highly active and selective for industrially relevant hydrosilylation of a broad range of substrates when a porous cage ligand is used for confinement around the catalytic active site. The catalyst is more than ten times more active than Karstedt’s catalyst while being recyclable. Properties such as size-selective catalysis and Michaelis-Menten kinetics support the proposed enzyme-like model. This biomimetic catalyst exhibits remarkable site-selectivity through the cage’s confining effect, which amplifies small steric differences into dramatic reactivity changes for similar functional groups within a molecule. Design of artificial catalysts to mimic enzyme activity and selectivity is a challenge in the catalysis field. Here, the authors design a platinum catalyst with a porous cage ligand which shows enzyme-like properties, such as high hydrosilylation activity and substrate size selectivity, while being recyclable.
ISSN:2041-1723
2041-1723
DOI:10.1038/s41467-020-20233-w