Low maternal iodine intake and early pregnancy hypothyroxinemia: Possible repercussions for children

Recent studies have shown that early pregnancy hypothyroxinemia (lower free thyroxin [FT4] and normal thyroid stimulating hormone [TSH] concentration) has deleterious effects on neuro-intellectual development of children. This study was designed to know its incidence in local pregnant women. Urinary...

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Bibliographic Details
Published in:Indian journal of endocrinology and metabolism 2014-07, Vol.18 (4), p.526-530
Main Authors: Elahi, Shan, Nagra, Saeed Ahmad
Format: Article
Language:English
Subjects:
Diagnosis
Fetuses
Hormones
Hospitals
Iodine
Laboratories
Maternal-fetal exchange
Medical research
Medicine, Experimental
Original
Pregnancy
Pregnancy, Complications of
Studies
Thyroid diseases
thyroid hormone
thyroid stimulating hormone
Urine
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Summary:Recent studies have shown that early pregnancy hypothyroxinemia (lower free thyroxin [FT4] and normal thyroid stimulating hormone [TSH] concentration) has deleterious effects on neuro-intellectual development of children. This study was designed to know its incidence in local pregnant women. Urinary iodine (UI) and serum thyroid related hormone (FT4, free triiodothyronine [FT3], and TSH) were determined in 254 pregnant women during the first trimester. UI and thyroid related hormones were determined by colorimetric (Sandell-Kolthoff) and radioimmunoassay method respectively. Most of the pregnant women (n = 202; 79.5%) were iodine deficient (ID; UI
ISSN:2230-8210
2230-9500
DOI:10.4103/2230-8210.137513