Healthy worker survival effect at a high-altitude mine: prospective cohort observation

Very little is known about the factors of healthy worker survival effect at high-altitude mines. We conducted this cohort observation of the new hires for a high-altitude gold mine in Kyrgyzstan with the aim to ascertain predictors of survival at work. All new hires in 2009 through 2012 for a high-a...

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Bibliographic Details
Published in:Scientific reports 2022-08, Vol.12 (1), p.13903-13903, Article 13903
Main Authors: Vinnikov, Denis, Krasotski, Viktor
Format: Article
Language:English
Subjects:
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Altitude
Blood pressure
Chronic obstructive pulmonary disease
Employment
Gold
Hemorrhoids
High-altitude environments
Humanities and Social Sciences
Hypertension
Lung diseases
multidisciplinary
New employees
Obstructive lung disease
Otitis
Physiology
Respiratory function
Rheumatic fever
Science
Science (multidisciplinary)
Sea level
Smoking
Survival
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Summary:Very little is known about the factors of healthy worker survival effect at high-altitude mines. We conducted this cohort observation of the new hires for a high-altitude gold mine in Kyrgyzstan with the aim to ascertain predictors of survival at work. All new hires in 2009 through 2012 for a high-altitude gold mine (3600–4500 m above sea level) were followed up to January 2022. We tested the association of demographic, physiological predictors and diagnoses at the pre-employment screening with non-survival at work in Cox proportional hazards yielding hazard ratios (HR) with their 95% confidence intervals (CI). The cumulative observation time was 5190 person-years. Blood pressure at pre-employment, lung function, the diagnoses of essential hypertension, chronic obstructive pulmonary disease (COPD) or any other analyzed physiological variables were not associated with non-survival at work. However, smoking (HR 1.55; 95% CI 1.10; 2.17) increased the likelihood of non-survival at work, independent of any diagnosis or lowland residence (HR 1.95; 95% CI 1.31; 2.90). Adjusted for covariates and all diagnoses, having chronic rheumatic fever (HR 10.95; 95% CI 2.92; 33.92), hemorrhoids (HR 1.32; 95% CI 1.01; 3.75), adhesive otitis (HR 1.74; 95% CI 1.05; 2.89) or obesity (HR 1.71; 95% CI 1.01; 2.88) were associated with non-survival at work with time. This prospective observation of new hires for a high-altitude mining operation demonstrated that selected diagnoses, smoking and lowland residence elevated the risk of early exit in prospective workers.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-18331-4