The effects of flip angle and gadolinium contrast agent on single breath-hold compressed sensing cardiac magnetic resonance cine for biventricular global strain assessment

• Published in: Frontiers in cardiovascular medicine 2024, Vol.11, p.1286271-1286271
• Main Authors: Wang, Fuyan, Pu, Cailing, Ma, Siying, Zhou, Junjie, Jiang, Yangyang, Yu, Feidan, Zhang, Shuheng, Wu, Yan, Zhang, Lingjie, He, Chengbin, Hu, Hongjie
• Format: Article
• Language: English
• Subjects: cardiovascular magnetic resonance; Cardiovascular Medicine; cine; compressed sensing; feature tracking; strain
• ISSN: 2297-055X; 2297-055X
• DOI: 10.3389/fcvm.2024.1286271

Due to its potential to significantly reduce scanning time while delivering accurate results for cardiac volume function, compressed sensing (CS) has gained traction in cardiovascular magnetic resonance (CMR) cine. However, further investigation is necessary to explore its feasibility and impact on myocardial strain results. A total of 102 participants [75 men, 46.5 ± 17.1 (SD) years] were included in this study. Each patient underwent four consecutive cine sequences with the same slice localization, including the reference multi-breath-hold balanced steady-state free precession (bSSFP ) cine, the CS cine with the same flip angle as bSSFP before (CS ) and after (eCS ) contrast enhancement, and the CS cine (eCS with a 70-degree flip angle after contrast enhancement. Biventricular strain parameters were derived from cine images. Two-tailed paired t-tests were used for data analysis. Global radial strain (GRS), global circumferential strain (GCS), and global longitudinal strain (GLS) were observed to be significantly lower in comparison to those obtained from bSSFP sequences for both the right and left ventricles (all