Association Between Elevated Blood Eosinophils and Chronic Kidney Disease Progression: Analyses of a Large United States Electronic Health Records Database

Blood eosinophils can increase in response to infection, inflammation, and hypersensitivity reactions, yet their involvement in the progression of chronic kidney disease (CKD) is poorly understood. This study explores the relationship between blood eosinophils and CKD progression among patients in a...

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Bibliographic Details
Published in:International journal of nephrology and renovascular disease 2023-01, Vol.16, p.269-280
Main Authors: Kielar, Danuta, Jones, Andrew M, Wang, Xia, Stirnadel-Farrant, Heide, Katial, Rohit K, Bansal, Abhinav, Garg, Manu, Sharma, Chandrakant, Thakar, Shubhankar, Ye, Qin
Format: Article
Language:English
Subjects:
Analysis
Anemia
Chronic kidney failure
Development and progression
Electronic records
eosinophilic inflammation
glomerular filtration rate
Health aspects
Hypertension
Medical records
Medical research
Medicine, Experimental
Original Research
Pharmaceutical industry
renal insufficiency
Risk factors
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Summary:Blood eosinophils can increase in response to infection, inflammation, and hypersensitivity reactions, yet their involvement in the progression of chronic kidney disease (CKD) is poorly understood. This study explores the relationship between blood eosinophils and CKD progression among patients in a real-world setting. This retrospective study analyzed data obtained from the Optum de-identified electronic health records dataset in the United States. Patients diagnosed with CKD stage 3 or 4 (International Classification of Diseases diagnosis code or estimated glomerular filtration rate [eGFR]
ISSN:1178-7058
1178-7058
DOI:10.2147/IJNRD.S431375