Renal venous sampling assisted the diagnosis of juxtaglomerular cell tumor: a case report and literature review

Juxtaglomerular cell tumor (JCT) is an endocrine tumor marked by elevated renin levels and high blood pressure. This case report presents the clinical findings of a 47-year-old woman with a history of recurrent hypokalemia, headaches, hypertension, and increased plasma renin activity (PRA). Dynamic...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in oncology 2024-01, Vol.13, p.1298684
Main Authors: Yan, Di-En, He, Hong-Bing, Guo, Jian-Ping, Wang, Yu-Lan, Peng, Dan-Ping, Zheng, Huan-Huan, Zhou, Xiao-Zi, Fu, Jin-Xiang, Wang, Mei-Li, Luo, Xian, Shen, Yun-Feng
Format: Article
Language:English
Subjects:
hypokalemia
juxtaglomerular cell tumor
Oncology
renal venous sampling
renin
resistant hypertension
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Juxtaglomerular cell tumor (JCT) is an endocrine tumor marked by elevated renin levels and high blood pressure. This case report presents the clinical findings of a 47-year-old woman with a history of recurrent hypokalemia, headaches, hypertension, and increased plasma renin activity (PRA). Dynamic enhanced magnetic resonance imaging (MRI) revealed a small nodule on the upper part of the right kidney. Selective renal venous sampling indicated a higher PRA only in the right upper pole renal vein. The patient underwent surgical removal of the right kidney mass, and the pathology results confirmed the diagnosis of JCT. This case underscores the importance of conducting selective renal venous sampling for accurate JCT diagnosis.
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2023.1298684