Data for functional MRI connectivity in transgender people with gender incongruence and cisgender individuals

• Published in: Data in brief 2020-08, Vol.31, p.105691-105691, Article 105691
• Main Authors: Uribe, Carme, Junque, Carme, Gómez-Gil, Esther, Abos, Alexandra, Mueller, Sven C., Guillamon, Antonio
• Format: Article
• Language: English
• Subjects: Functional MRI; gender identity; gender incongruence; graph theory; independent component analysis (ICA); Medicine and Dentistry; resting-state connectivity; seed-based analysis; transmen; transwomen
• ISSN: 2352-3409; 2352-3409
• DOI: 10.1016/j.dib.2020.105691

We provide T2*-weighted and T1-weighted images acquired on a 3T MRI scanner obtained from 17 transwomen and 29 transmen with gender incongruence; and 22 ciswomen and 19 cismen that identified themselves to the sex assigned at birth. Data from three different techniques that describe global and regional connectivity differences within functional resting-state networks in transwomen and transmen with early-in-life onset gender incongruence are provided: (1) we obtained spatial maps from data-driven independent component analysis using the melodic tool from FSL software; (2) we provide the functional networks interactions of two functional atlases’ seeds from a seed-to-seed approach; (3) and global graph-theoretical metrics such as the smallworld organization, and the segregation and integration properties of the networks. Interpretations of the present dataset can be found in the original article, doi:10.1016/j.neuroimage.2020.116613[1]. The original and processed nifti images are available in Mendeley datasets. In addition, correlation matrices for the seed-to-seed and graph-theory analyses as well as the graph-theoretical measures were made available in Matlab files. Finally, we present supplementary information for the original article.