Deep Vein Thrombosis after Lithium Toxicity: A Report of Two Cases and Literature Review

Lithium administration can reportedly cause toxicity, including lithium-associated thrombosis; however, not all reported cases of this adverse effect have been attributable to lithium overdoses. We report here two cases of deep vein thrombosis that occurred in association with lithium toxicity. Lith...

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Bibliographic Details
Published in:Case reports in psychiatry 2021, Vol.2021, p.1-4
Main Authors: Sogawa, Rintaro, Tobita, Shuko, Monji, Akira, Murakawa-Hirachi, Toru, Mizoguchi, Yoshito, Sakamoto, Yuichiro, Irie, Hiroyuki, Shimanoe, Chisato
Format: Article
Language:English
Subjects:
Bipolar disorder
Case Report
Case reports
Catheters
Compression therapy
Consciousness
Creatinine
Glasgow Coma Scale
Hemodialysis
Hospitalization
Joint replacement surgery
Joint surgery
Knee
Lithium
Nausea
Patients
Proteins
Psychotropic drugs
Rehabilitation
Risk factors
Thromboembolism
Thrombosis
Ultrasonic imaging
Veins & arteries
Vomiting
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Summary:Lithium administration can reportedly cause toxicity, including lithium-associated thrombosis; however, not all reported cases of this adverse effect have been attributable to lithium overdoses. We report here two cases of deep vein thrombosis that occurred in association with lithium toxicity. Lithium overdose was deemed to be the cause in only one of these cases; a patient in whom deep vein thrombosis occurred 11 days after identification of lithium toxicity. In the other patient, the deep vein thrombosis occurred 15 days after diagnosis of lithium toxicity; this patient was not considered to have been overdosed. Both patients had other risk factors in addition to receiving lithium. We recommend monitoring D-dimer concentrations to facilitate early detection of deep vein thrombosis in patients with lithium toxicity.
ISSN:2090-682X
2090-6838
DOI:10.1155/2021/9934037