Xanthone Glucosides: Isolation, Bioactivity and Synthesis

Xanthones are secondary metabolites found in plants, fungi, lichens, and bacteria from a variety of families and genera, with the majority found in the Gentianaceae, Polygalaceae, and Clusiaceae. They have a diverse range of bioactivities, including anti-oxidant, anti-bacterial, anti-malarial, anti-...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2021-09, Vol.26 (18), p.5575
Main Authors: Huang, Qing, Wang, Youyi, Wu, Huaimo, Yuan, Man, Zheng, Changwu, Xu, Hongxi
Format: Article
Language:English
Subjects:
9H-xanthen-9-one
Antioxidants
Antioxidants - chemistry
Antioxidants - pharmacology
Binding sites
Biological activity
chemical synthesis
Cytotoxicity
Diabetes
Free radicals
Glucose
Glucosides
Glucosides - chemistry
Glucosides - isolation & purification
Glucosides - pharmacology
Glycosylation
Humans
Lichens
Literature reviews
Metabolites
Molecular Structure
Oxidants
Oxidizing agents
pharmacological activity
Review
Secondary metabolites
Tuberculosis
xanthone C-glucoside
xanthone O-glucoside
Xanthones - chemistry
Xanthones - isolation & purification
Xanthones - pharmacology
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Summary:Xanthones are secondary metabolites found in plants, fungi, lichens, and bacteria from a variety of families and genera, with the majority found in the Gentianaceae, Polygalaceae, and Clusiaceae. They have a diverse range of bioactivities, including anti-oxidant, anti-bacterial, anti-malarial, anti-tuberculosis, and cytotoxic properties. Xanthone glucosides are a significant branch of xanthones. After glycosylation, xanthones may have improved characteristics (such as solubility and pharmacological activity). Currently, no critical review of xanthone glucosides has been published. A literature survey including reports of naturally occurring xanthone glucosides is included in this review. The isolation, structure, bioactivity, and synthesis of these compounds were all explored in depth.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules26185575