Three Cases of Arteritic Anterior Optic Neuropathy Several Months after COVID-19 Vaccination

Background. Vaccines have been approved worldwide to control the coronavirus disease-19 (COVID-19). However, the postvaccination side effects remain controversial. Here, we describe three Japanese cases of arteritic anterior ischaemic optic neuropathy (AAION) following COVID-19 vaccination. Case pre...

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Bibliographic Details
Published in:Case reports in ophthalmological medicine 2023-09, Vol.2023, p.1-6
Main Authors: Yamamoto, Yuichi, Ogino, Ken, Yasuhara, Satoshi, Kawashima, Yu, Miki, Toshiya
Format: Article
Language:English
Subjects:
Antibodies
Biopsy
Blood
Blood tests
C-reactive protein
Cartilage
Case Report
Case reports
Coronaviruses
COVID-19 vaccines
Headaches
Hospitals
Ischemia
Magnetic resonance imaging
Medical examination
Microscopy
mRNA vaccines
Neutrophils
Optic nerve
Steroids
Vaccination
Vein & artery diseases
Visual acuity
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Summary:Background. Vaccines have been approved worldwide to control the coronavirus disease-19 (COVID-19). However, the postvaccination side effects remain controversial. Here, we describe three Japanese cases of arteritic anterior ischaemic optic neuropathy (AAION) following COVID-19 vaccination. Case presentation. The first case involved an 87-year-old woman who presented with vision loss in the right eye 2 months after her second COVID-19 vaccine and in the left eye 2 days later. The second case involved an 88-year-old woman who presented with vision loss in both eyes 3 months after receiving a second vaccine. The third case involved an 80-year-old man who presented with vision loss in the right eye 5 months after receiving a second vaccine. The C-reactive protein level and erythrocyte sedimentation rate were elevated in all patients. Biopsy of the temporal artery or auricular cartilage showed arteritic occlusion in case 2 and polychondritis in case 3. These patients were referred to a local Japanese hospital in 2021 over a period of no longer than 3 months. Conclusion. We observed three cases of AAION after the affected individuals received their second COVID-19 vaccine. Further long-term investigations of ophthalmological events after COVID-19 vaccination are warranted.
ISSN:2090-6722
2090-6730
DOI:10.1155/2023/8845850