Insights on the Pooled Prevalence and Global Distribution of Leptospirosis in Goats: Systematic Review and Meta-Analysis

• Published in: Microorganisms (Basel) 2024-11, Vol.12 (12), p.2391
• Main Authors: de Araújo Portela, Roseane, Limeira, Clécio Henrique, Bezerra, José Artur Brilhante, Martins, Camila Marinelli, da Costa, Diego Figueiredo, Santos, Carolina de Sousa Américo Batista, Alves, Clebert José, Azevedo, Sérgio Santos de
• Format: Article
• Language: English
• Subjects: Animals; Antigens; Arid climates; Arid regions; Aridity; Bias; Contamination; diagnosis; Disease control; Economic impact; Environmental management; Goats; Health aspects; Heterogeneity; Immunization; Impact analysis; Infection; Infections; International marketing; Leptospira; Leptospira spp; Leptospirosis; Livestock farming; Livestock farms; MAT; Meta-analysis; Polymerase chain reaction; Public health; Review; Reviews; Risk factors; serogroup; Serology; serovar; small ruminants; Software; Systematic review
• ISSN: 2076-2607; 2076-2607
• DOI: 10.3390/microorganisms12122391

spp. infection in small ruminants is usually asymptomatic or presents nonspecific clinical signs and has an economic impact on goat farming and public health. The aim of this study was to carry out a systematic review with meta-analysis on the global seroprevalence and distribution of leptospirosis in goats. The methodology was based on the recommendations of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), and the review project was registered in the International Prospective Register of Systematic Reviews (PROSPERO-ID: CRD42023405693). Overall, 79 articles were included in the study. The global prevalence of leptospirosis in goats was 18.6% (CI 95% = 15.08-22.71%), with no publication bias and high heterogeneity. The records originated from South America (n = 32), Asia (n = 26), Europe (n = 8), North America (n = 7), and Africa (n = 6), and seropositivities were 17%, 19%, 12%, 34%, and 22%, respectively. It is concluded that spp. infection is widespread in goat herds, including regions with semi-arid and arid climates, and it is suggested that the prospects for controlling the disease should focus on avoiding environmental contamination and improving management measures and sanitary practices. This important information provides guidance for actions to protect against human contamination and to control animal leptospirosis.