Intragastric injection of botulinum toxin in the treatment of obesity: a single-center study

In recent years, various novel surgical and non-surgical therapeutic options have been developed for treating obesity. Due to its disputed success, intragastric botulinum toxin A (BTX-A) injection is still being debated. We aim to contribute to this controversial issue in the literature by sharing o...

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Published in:Therapeutic advances in gastrointestinal endoscopy 2024-01, Vol.17, p.26317745241233083-26317745241233083
Main Authors: Köseoğlu, Hasan Tankut, Kenarli, Kerem, Akbay, Ahmet, Erdoğan, Çağdaṣ, Macif, Alper, Göktaṣ, Meryem Didem, Hamamci, Mevlüt, Kalkan, Çağdaṣ, Sarialtin, Firathan, Yüksel, Mahmut
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Language:English
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Summary:In recent years, various novel surgical and non-surgical therapeutic options have been developed for treating obesity. Due to its disputed success, intragastric botulinum toxin A (BTX-A) injection is still being debated. We aim to contribute to this controversial issue in the literature by sharing our center's findings regarding intragastric BTX-A injections in the treatment of obesity. Patients with a body mass index (BMI) of greater than 25 kg/m and at least one obesity-related complication, or a BMI of greater than 30 kg/m without complications, were eligible for the study if they were between the ages of 18 and 65. Following the same procedure, two endoscopists administered BTX-A to all patients. All patients were evaluated for obesity by measuring their lipid profile, hormone profile, and insulin resistance level before treatment. In our study on 82 patients, we saw a significant mean weight loss (-9.2 kg,  
ISSN:2631-7745
2631-7745
DOI:10.1177/26317745241233083