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The EWAS Catalog: a database of epigenome-wide association studies

Epigenome-wide association studies (EWAS) seek to quantify associations between traits/exposures and DNA methylation measured at thousands or millions of CpG sites across the genome. In recent years, the increase in availability of DNA methylation measures in population-based cohorts and case-contro...

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Published in:Wellcome open research 2022-01, Vol.7, p.41-41
Main Authors: Battram, Thomas, Yousefi, Paul, Crawford, Gemma, Prince, Claire, Sheikhali Babaei, Mahsa, Sharp, Gemma, Hatcher, Charlie, Vega-Salas, María Jesús, Khodabakhsh, Sahar, Whitehurst, Oliver, Langdon, Ryan, Mahoney, Luke, Elliott, Hannah R., Mancano, Giulia, Lee, Matthew A., Watkins, Sarah H., Lay, Abigail C., Hemani, Gibran, Gaunt, Tom R., Relton, Caroline L., Staley, James R., Suderman, Matthew
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Language:English
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Summary:Epigenome-wide association studies (EWAS) seek to quantify associations between traits/exposures and DNA methylation measured at thousands or millions of CpG sites across the genome. In recent years, the increase in availability of DNA methylation measures in population-based cohorts and case-control studies has resulted in a dramatic expansion of the number of EWAS being performed and published. To make this rich source of results more accessible, we have manually curated a database of CpG-trait associations (with p
ISSN:2398-502X
2398-502X
DOI:10.12688/wellcomeopenres.17598.2