Antioxidant and Antibacterial Activities of Chinese Native Thyme Essential Oils with Different Chemotypes

• Published in: Molecules (Basel, Switzerland) Switzerland), 2024-12, Vol.29 (24), p.6035
• Main Authors: Sun, Meiyu, Zhang, Yanan, Hao, Yuanpeng, Miao, Jiahui, Sun, Guofeng, Xiao, Jianhua, Yang, Xiao, Zhang, Jinzheng, Shi, Lei
• Format: Article
• Language: English
• Subjects: Analysis; antibacterial activity; Antibacterial agents; Antibiotics; Antifungal agents; Antimicrobial agents; antioxidant activity; Antioxidants; Antiviral agents; Bacteria; Bacterial infections; chemotype; Chinese native thyme; Correlation analysis; Cosmetics; E coli; Escherichia coli; essential oil; Food additives; Food contamination & poisoning; Oils & fats; Pharmaceuticals; Preservatives; Product development
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules29246035

Thyme essential oils (EOs) have antioxidant, antiviral, antifungal, antibacterial, anti-inflammatory, and immunological properties and are used in medicine, food, feed additives, and cosmetics. Here, we made use of a multidimensional analytical method to analyze the differences in the chemical components, chemotypes, and antioxidant and antibacterial activities of EOs from 24 Chinese native thymes. These Chinese native thymes comprised 10 species (Thymus quinquecostatus, T. mongolicus, T. inaequalis, T. mandschuricus, T. curtus, T. amurensis, T. roseus, T. proximu, T. marschallianus, and T. altaicus) and two varieties (T. quinquecostatus var. asiaticus and T. quinquecostatus var. przewalskii). Four primary chemotype groups were identified, namely carvacrol, thymol, geraniol, and α-terpineol. The maximum carvacrol, thymol, geraniol, and α-terpineol contents were 72.4, 58.6, 59.5, and 65.4%, respectively. The antioxidant capacities of the thymol and carvacrol chemotype EOs were found to be significantly superior to the other chemotypes using three antioxidant assays: DPPH, ABTS, and FRAP. Moreover, the thymol and carvacrol EO chemotypes could significantly inhibit the growths of the common food-borne pathogenic bacteria Staphylococcus aureus and Escherichia coli. A correlation analysis between the EO components and the bacteria showed that thymol significantly positively correlated with the bacteria. In summary, we analyzed the thyme EOs’ antioxidant and antibacterial activities, which laid a foundation for their use in medicines, foods, feed additives, and cosmetics. The results will also be very useful for the selection of wild thymes for functional research on carvacrol-, thymol-, geraniol-, and α-terpineol-rich essential oil chemotypes and the product development of feed additives, cosmetics, etc.