Relationship of urinary glyphosate concentrations with glycosylated hemoglobin and diabetes in US adults: a cross-sectional study

Glyphosate is a commonly used herbicide worldwide and is purportedly associated with multiple health effects. Research assessing the association of glyphosate concentrations with glycosylated hemoglobin (HbA1c) levels and the prevalence of diabetes is scarce. We sought to evaluate the association be...

Full description

Saved in:
Bibliographic Details
Published in:BMC public health 2024-06, Vol.24 (1), p.1644-10, Article 1644
Main Authors: Tang, Peng, Wang, Yican, Liao, Qian, Zhou, Yong, Huang, Huishen, Liang, Jun, Zeng, Xiaoyun, Qiu, Xiaoqiang
Format: Article
Language:English
Subjects:
Adult
Adults
Aged
Agricultural production
Alcohol
Analysis
Body mass index
Creatinine
Cross-Sectional Studies
Diabetes
Diabetes mellitus
Diabetes Mellitus - epidemiology
Dose-Response Relationship, Drug
Evaluation
Exercise
Female
Generalized linear models
Glucose
Glycated Hemoglobin - analysis
Glycine - analogs & derivatives
Glycine - urine
Glycosylated hemoglobin
Glyphosate
Health aspects
Hemoglobin
Herbicides
Herbicides - urine
Humans
Male
Measurement
Metabolism
Middle Aged
NHANES
Nutrition Surveys
Population
Prevalence
Quartiles
Risk factors
Secondary schools
Self report
Smoking
Spline functions
Statistical analysis
Statistical models
Statistics
United States - epidemiology
Urine
Young Adult
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Glyphosate is a commonly used herbicide worldwide and is purportedly associated with multiple health effects. Research assessing the association of glyphosate concentrations with glycosylated hemoglobin (HbA1c) levels and the prevalence of diabetes is scarce. We sought to evaluate the association between urinary glyphosate levels and HbA1c levels and the prevalence of diabetes. A total of 2,745 adults in the National Health and Nutrition Examination Survey from 2013 to 2016 were included in this study. Generalized linear models (GLM) were applied to evaluate the associations of glyphosate concentrations with HbA1c levels and the prevalence of diabetes. The dose-response relationship was examined using restricted cubic splines (RCS). Significantly positive correlations of urinary glyphosate concentrations with HbA1c levels (percentage change: 1.45; 95% CI: 0.95, 1.96; P 
ISSN:1471-2458
1471-2458
DOI:10.1186/s12889-024-19126-0