Lipoprotein(a), high-sensitivity c-reactive protein, homocysteine and cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis

Elevated lipoprotein(a) [Lp(a)], high-sensitivity C-Reactive Protein (hs-CRP), and total homocysteine (tHcy) are associated with atherosclerotic cardiovascular disease (ASCVD) risk. This study investigated the individual and joint associations of Lp(a), hs-CRP and tHcy with coronary heart disease (C...

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Bibliographic Details
Published in:American journal of preventive cardiology 2025-03, Vol.21, p.100903, Article 100903
Main Authors: Nomura, Sarah O., Bhatia, Harpreet S., Garg, Parveen K., Karger, Amy B., Guan, Weihua, Cao, Jing, Shapiro, Michael D., Tsai, Michael Y.
Format: Article
Language:English
Subjects:
Coronary heart disease
High-sensitivity c-reactive protein
Homocysteine
Lipoprotein(a)
Stroke
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Summary:Elevated lipoprotein(a) [Lp(a)], high-sensitivity C-Reactive Protein (hs-CRP), and total homocysteine (tHcy) are associated with atherosclerotic cardiovascular disease (ASCVD) risk. This study investigated the individual and joint associations of Lp(a), hs-CRP and tHcy with coronary heart disease (CHD) and stroke. This study was conducted in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort (2000–2017) (CHD analytic N = 6,676; stroke analytic N = 6,674 men and women). Associations between Lp(a) (
ISSN:2666-6677
2666-6677
DOI:10.1016/j.ajpc.2024.100903