Effects of Two Different Dosages of Sildenafil on Patients With Erectile Dysfunction

• Published in: American journal of men's health 2017-05, Vol.11 (3), p.525-530
• Main Authors: Li, Hongjun, Bai, Gang, Zhang, Xinyu, Shi, Bingbing, Liu, Defeng, Jiang, Hui, Ji, Zhigang, Davis, Matthew R., Zhu, Ziwen, Fang, Yujiang
• Format: Article
• Language: English
• Subjects: Adult; Age Distribution; Dose-Response Relationship, Drug; Erectile dysfunction; Erectile Dysfunction - drug therapy; Humans; Male; Middle Aged; Product safety; Sildenafil Citrate - administration & dosage; Surveys and Questionnaires; Vasodilator Agents - administration & dosage
• ISSN: 1557-9883; 1557-9891
• DOI: 10.1177/1557988315620467

To investigate the effects of two different dosages of sildenafil on patients with erectile dysfunction (ED), a total of 3,674 patients with ED were recruited to answer questionnaires designed specifically for this study. There were 977 patients in the 50 mg group and there were 2,697 patients in the 100 mg group. Both 50 mg and 100 mg of sildenafil therapy increased the ED patients’ average monthly frequency of sexual intercourse, improved erectile function state in self-assessment, and elevated sexual satisfaction and enjoyment. Despite a higher rate of concomitant diseases, patients in the higher dosage of sildenafil group had a better outcome in the average monthly frequency of sexual intercourse and sexual enjoyment compared with those in the lower dosage. Such a study might be helpful for health care providers to choose sildenafil dosage for patients with ED.