Biological Activity of Pulcherrimin from the Meschnikowia pulcherrima Clade

Pulcherrimin is a secondary metabolite of yeasts belonging to the clade, and pulcherrimin formation is responsible for the antimicrobial action of its producers. Understanding the environmental function of this metabolite can provide insight into various microbial interactions and enables the effici...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2022-03, Vol.27 (6), p.1855
Main Authors: Kregiel, Dorota, Nowacka, Maria, Rygala, Anna, Vadkertiová, Renáta
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents
antibiofilm
Antiinfectives and antibacterials
Antimicrobial agents
Biological activity
Bone Plates
Cold Temperature
Genomes
Hydrophilicity
Iron
Low temperature
Metabolites
Metschnikowia
Microbial Interactions
Microbiological Techniques
Microorganisms
protection
pulcherrimin
Spectrum analysis
Taxonomy
UV–C light
water affinity
Yeast
Yeasts
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Summary:Pulcherrimin is a secondary metabolite of yeasts belonging to the clade, and pulcherrimin formation is responsible for the antimicrobial action of its producers. Understanding the environmental function of this metabolite can provide insight into various microbial interactions and enables the efficient development of new effective bioproducts and methods. In this study, we evaluated the antimicrobial and antiadhesive action of yeast pulcherrimin, as well as its protective properties under selected stressful conditions. Classical microbiological plate methods, microscopy, and physico-chemical testing were used. The results show that pure pulcherrimin does not have antimicrobial properties, but its unique hydrophilic nature may hinder the adhesion of hydrophilic bacterial cells to abiotic surfaces. Pulcherrimin also proved to be a good cell protectant against UV-C radiation at both high and low temperatures.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules27061855