Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient Habits

Hidradenitis suppurativa (HS) is a debilitating, chronic, inflammatory skin disease primarily affecting apocrine gland-rich areas of the body. On the one hand, the presence of triggering factors-some identified, others only hypothesized-may initiate or perpetuate the pathogenic process of HS. In add...

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Bibliographic Details
Published in:Biomedicines 2022-11, Vol.10 (11), p.2973
Main Authors: Rosi, Elia, Fastame, Maria Thais, Silvi, Gianmarco, Guerra, Prisca, Nunziati, Giulia, Di Cesare, Antonella, Scandagli, Ilaria, Ricceri, Federica, Prignano, Francesca
Format: Article
Language:English
Subjects:
African Americans
Breast feeding
Cigarette smoking
Cigarettes
Cultural differences
diet
Disease
Drug abuse
Epidemiology
Females
Gender
Gender differences
habits
hidradenitis suppurativa
Males
Nicotine
Pathophysiology
Patients
Physiological aspects
Quality of life
Race
Review
Sex differences
Skin
Skin diseases
Smoking
Tobacco
trigger factors
Vaping
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Summary:Hidradenitis suppurativa (HS) is a debilitating, chronic, inflammatory skin disease primarily affecting apocrine gland-rich areas of the body. On the one hand, the presence of triggering factors-some identified, others only hypothesized-may initiate or perpetuate the pathogenic process of HS. In addition to cigarette smoking and diet, other trigger factors, including choice of clothing, are frequently observed in clinical practice. On the other hand, the presence of disease may influence habits of HS patients. Indeed, high incidences of sexual and sleep impairment have been reported in these patients. Consequently, alcohol and substance abuse may be a coping strategy for the emotional and psychological disease burden. Furthermore, a greater awareness of gender differences in HS may be important for dermatologists in their own clinical practice (i.e., pregnancy and breastfeeding). Consequently, in this loop interaction, comprehensive knowledge of all factors involved is crucial for the management of HS patients. Thus, the objective of this review is to (i) discuss the influence of gender on HS, (ii) summarize the most frequent triggering factors of HS and (iii) analyze the impact of HS on patient habits.
ISSN:2227-9059
2227-9059
DOI:10.3390/biomedicines10112973