Herpes Gestationis after Ovodonation: Is Placenta the only Target of the Immune Reaction?

Herpes Gestationis (HG) is an autoimmune disorder that rarely complicates pregnancy. Its pathogenesis has not been clarified yet, as it derives from a complex interplay between immunologic, genetic, and hormonal factors. We present a case of HG occurring in a surrogate mother whose pregnancy was ach...

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Bibliographic Details
Published in:Journal of clinical and diagnostic research 2014-11, Vol.8 (11), p.OD01-OD02
Main Authors: Piva, Isabella, Lo Monte, Giuseppe, Graziano, Angela, Marci, Roberto
Format: Article
Language:English
Subjects:
autoimmunity
dermatoses of pregnancy
herpes gestationis
Obstetrics and Gynaecology Section
ovodonation
prurigo gestationis
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Summary:Herpes Gestationis (HG) is an autoimmune disorder that rarely complicates pregnancy. Its pathogenesis has not been clarified yet, as it derives from a complex interplay between immunologic, genetic, and hormonal factors. We present a case of HG occurring in a surrogate mother whose pregnancy was achieved via egg donation and in vitro fertilisation (IVF). The disease appeared at 26 weeks and 6 days of gestation and subsequently worsened despite the administration of oral and topic corticosteroids. A healthy baby was delivered at 35 weeks and 2 days of gestation by elective cesarean section and the clinical manifestations resolved in the postpartum period.
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2014/8727.5103