The hidden risk: Intracranial hemorrhage following durotomies in spine surgery

• Published in: North American Spine Society journal (NASSJ) 2024-12, Vol.20, p.100555, Article 100555
• Main Authors: Gerstmeyer, Julius, Avantaggio, August, Pierre, Clifford, Patel, Neel, Davis, Donald D., Anderson, Bryan, Godolias, Periklis, Schildhauer, Thomas, Abdul-Jabbar, Amir, Oskouian, Rod J., Chapman, Jens R.
• Format: Article
• Language: English
• Subjects: Clinical Studies; Dural tear; Durotomy; Intracranial hemorrhage; Postoperative cerebrospinal fluid leakage; Spinal surgery
• ISSN: 2666-5484; 2666-5484
• DOI: 10.1016/j.xnsj.2024.100555

Intracranial hemorrhage (ICH) after durotomy in elective spine surgery, though rare, can pose a significant risk to patient outcomes. Spine surgeries bear a risk of dural tears (DT) with potential of postoperative cerebrospinal fluid leakage (PCSFL). Excessive PCSFL can precipitate a decrease in intracranial pressure, potentially leading to ICH. Literature on ICH as a postoperative complication is scarce. The aim was to assess the incidence and risk factors of ICH in patients undergoing elective spine surgery. Utilizing the 2020 National Impatient Sample (NIS) adults (>18 years) were selected by primary procedure category codes for spine fusion, discectomy, spinal cord decompression and cervicothoracic/lumbosacral nerve decompression. Exclusion criteria were trauma and malignancy. The primary outcome was occurrence of ICH. Comparative analysis and a multivariable logistic regression were used to identify independent risk. In total, 40,990 patients met our criteria with an incidence of ICH at 0.08%. The ICH-group showed an increased length of stay and higher mortality compared to the control group. Spinal cord decompression, DT and PCSFL were significantly more frequent in patients with ICH. Alcohol, drug abuse and hypertension were significantly more prevalent in patients with ICH. DT, alcohol abuse and hypertension were independent risk factors for ICH. This study underscores the rarity and severity of ICHs following elective spine surgery, emphasizing awareness and looking for possible preventive measures. Our finding suggests that DT, as a complication of surgical techniques, as well as alcohol abuse and hypertension are significant predictors of ICH.