Osteoarthritis or arthritis? Toward understanding of primary Sjögren's syndrome patients with arthralgia

To identify primary Sjögren's syndrome (pSS) patients with arthralgia at risk for osteoarthritis (OA) or arthritis. This study included 368 pSS patients admitted to a mono-centric from March 2010 to December 2020. Patients were divided into groups according to whether complicated with OA or art...

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Published in:Journal of orthopaedic surgery and research 2023-01, Vol.18 (1), p.41-41, Article 41
Main Authors: Gao, Ronglin, Pu, Jincheng, Wu, Zhenzhen, Tang, Jianping, Wang, Xuan
Format: Article
Language:English
Subjects:
Arthralgia
Arthralgia - diagnosis
Arthralgia - etiology
Arthritis
Humans
Joint pain
Lipids
Medical research
Medicine, Experimental
Metabolism
Metacarpophalangeal Joint
Osteoarthritis
Osteoarthritis - complications
Primary Sjögren’s syndrome
Sjogren's Syndrome - complications
Sjogren's Syndrome - diagnosis
Uric Acid
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Summary:To identify primary Sjögren's syndrome (pSS) patients with arthralgia at risk for osteoarthritis (OA) or arthritis. This study included 368 pSS patients admitted to a mono-centric from March 2010 to December 2020. Patients were divided into groups according to whether complicated with OA or arthritis. Data were analyzed to determine the differences in demographical characteristics, symptoms, and laboratory examination. The involvement of the OA joints was predominately knee and spine sites (including cervical and lumbar spine degeneration). When diagnosing arthritis, it was mainly peripheral symmetric polyarthritis, the most affected sites were the interphalangeal and metacarpophalangeal joints. There were significant differences in age, disease duration, uric acid (UA), and total cholesterol (TC) between pSS-OA and pSS-nOA patients (P 
ISSN:1749-799X
1749-799X
DOI:10.1186/s13018-023-03513-1