Progress of near-infrared-II fluorescence in precision diagnosis and treatment of colorectal cancer

Colorectal cancer is a malignant tumour with high incidence and mortality worldwide; therefore, improving the early diagnosis of colorectal cancer and implementing a targeted "individualized treatment" strategy is of great concern. NIR-II fluorescence imaging is a large-depth, high-resolut...

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Bibliographic Details
Published in:Heliyon 2023-12, Vol.9 (12), p.e23209-e23209, Article e23209
Main Authors: Wu, Yong, Cao, Hongtao, Yang, Shaoqing, Liu, Chaohui, Han, Zhenguo
Format: Article
Language:English
Subjects:
colorectal cancer
NIR-II
precision diagnosis and treatment
Review
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Summary:Colorectal cancer is a malignant tumour with high incidence and mortality worldwide; therefore, improving the early diagnosis of colorectal cancer and implementing a targeted "individualized treatment" strategy is of great concern. NIR-II fluorescence imaging is a large-depth, high-resolution optical bioimaging tool. Around the NIR-II window, researchers have developed a variety of luminescent probes, imaging systems, and treatment methods with colorectal cancer targeting capabilities, which can be visualized and image-guided in clinical surgery. This article aims to overcome the difficulties in diagnosing and treating colorectal cancer. The present review summarizes the latest results on using NIR-II fluorescence for targeted colorectal cancer imaging, expounds on the application prospects of NIR-II optical imaging for colorectal cancer, and discusses the imaging-guided multifunctional diagnosis and treatment platforms.
ISSN:2405-8440
2405-8440
DOI:10.1016/j.heliyon.2023.e23209