Enhancement in mechanical and antimicrobial properties of epoxidized natural rubber via reactive blending with chlorhexidine gluconate

An epoxidized natural rubber (ENR) blend with chlorhexidine gluconate (CHG) was prepared using a two-roll mill at 130 °C. CHG was added at concentrations of 0.2, 0.5, 1, 2, 5, and 10% (w/w) as an antimicrobial additive. The ENR blend with 10% (w/w) CHG showed the best tensile strength, elastic recov...

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Bibliographic Details
Published in:Scientific reports 2023-06, Vol.13 (1), p.9974-9974, Article 9974
Main Authors: Kanthiya, Thidarat, Thajai, Nanthicha, Chaiyaso, Thanongsak, Rachtanapun, Pornchai, Thanakkasaranee, Sarinthip, Kumar, Anbarasu, Boonrasri, Siwarote, Kittikorn, Thorsak, Phimolsiripol, Yuthana, Leksawasdi, Noppol, Tanadchangsaeng, Nuttapol, Jantanasakulwong, Kittisak
Format: Article
Language:English
Subjects:
631/61
639/301
639/638
Amino groups
Anti-Infective Agents - pharmacology
Antimicrobial agents
Bacteria
Biomedical materials
Chlorhexidine
Chlorhexidine - pharmacology
Fourier transforms
Fractures
Gram-positive bacteria
Heat resistance
Hot pressing
Humanities and Social Sciences
Mechanical properties
Morphology
multidisciplinary
Polymers
Rubber
Science
Science (multidisciplinary)
Tensile Strength
Vegetable oils
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Summary:An epoxidized natural rubber (ENR) blend with chlorhexidine gluconate (CHG) was prepared using a two-roll mill at 130 °C. CHG was added at concentrations of 0.2, 0.5, 1, 2, 5, and 10% (w/w) as an antimicrobial additive. The ENR blend with 10% (w/w) CHG showed the best tensile strength, elastic recovery, and Shore A hardness. The ENR/CHG blend exhibited a smooth fracture surface. The appearance of a new peak in the Fourier transform infrared spectrum confirmed that the amino groups of CHG reacted with the epoxy groups of ENR. The ENR with 10% CHG exhibited an inhibition zone against Staphylococcus aureus . The proposed blending improved the mechanical properties, elasticity, morphology, and antimicrobial properties of the ENR.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-36962-z