Epithelioid angiomyolipoma of the liver: a case report

Epithelioid angiomyolipoma (EAML) of liver is a rare neoplasm. Hepatic EAML is often misdiagnosed as other neoplasms such as hepatocellular carcinoma due to non-specific clinical and radiologic features. The morphologic features under microscope and immunohistochemistry staining profile are importan...

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Bibliographic Details
Published in:Clinical and molecular hepatology 2017-03, Vol.23 (1), p.91-94
Main Authors: Lee, Soo Yeon, Kim, Baek-Hui
Format: Article
Language:English
Subjects:
Angiomyolipoma
Angiomyolipoma - diagnostic imaging
Angiomyolipoma - pathology
Antigens
Body fat
Case reports
Cytoplasm
Humans
Hyperplasia
Immunohistochemistry
Liver
Liver - diagnostic imaging
Liver - pathology
Liver cancer
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - pathology
Male
MART-1 Antigen - metabolism
Melanoma-Specific Antigens - metabolism
Metastasis
Microscopy, Fluorescence
Middle Aged
Perivascular epithelioid cell neoplasms
Smooth muscle
Stains & staining
Tomography
Tomography, X-Ray Computed
Tuberous sclerosis
Tumors
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Summary:Epithelioid angiomyolipoma (EAML) of liver is a rare neoplasm. Hepatic EAML is often misdiagnosed as other neoplasms such as hepatocellular carcinoma due to non-specific clinical and radiologic features. The morphologic features under microscope and immunohistochemistry staining profile are important in the diagnosis EAML. Here, we report a case of 52-year-old man who found 1.2 cm mass in liver by routine checkup. On the impression of hepatocellular carcinoma, lateral sectionectomy of the liver was done. Microscopically, the tumor is composed of predominant epithelioid cells with vascular component and foamy cells. These cells were positive for HMB45, MelanA, and smooth muscle actin and negative for epithelial membrane antigen. The final diagnosis was hepatic EAML.
ISSN:2287-2728
2287-285X
DOI:10.3350/cmh.2017.0011