Elevated levels of cortisol in hair precede acute myocardial infarction

Long term stress exposure is typical for modern societies and might trigger different diseases. This case–control study reveals that persons who had suffered an acute myocardial infarction (AMI) had elevated cortisol concentrations in the month before the acute event. Middle-aged patients admitted t...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2020-12, Vol.10 (1), p.22456-22456, Article 22456
Main Authors: Faresjö, Tomas, Strömberg, Susanna, Jones, Mike, Stomby, Andreas, Karlsson, Jan-Erik, Östgren, Carl Johan, Faresjö, Åshild, Theodorsson, Elvar
Format: Article
Language:English
Subjects:
692/4019
692/499
692/53
Aged
Biomarkers
Cardiometabolic Risk Factors
Cardiovascular diseases
Case-Control Studies
Cortisol
Female
Hair
Hair - metabolism
Health risks
Heart attacks
Hormones
Humanities and Social Sciences
Humans
Hydrocortisone - blood
Hydrocortisone - metabolism
Male
Middle age
Middle Aged
multidisciplinary
Multivariate analysis
Myocardial infarction
Myocardial Infarction - etiology
Myocardial Infarction - metabolism
Odds Ratio
Risk factors
Science
Science (multidisciplinary)
Statistical analysis
Stress, Physiological
Stress, Psychological
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Long term stress exposure is typical for modern societies and might trigger different diseases. This case–control study reveals that persons who had suffered an acute myocardial infarction (AMI) had elevated cortisol concentrations in the month before the acute event. Middle-aged patients admitted to cardiology clinics with acute myocardial infarction (AMI) (n = 174) were compared to 3156 controls from a population-based cohort in southeast Sweden. The median Hair Cortisol Concentrations (HCC) for those who had suffered an AMI was 53.2 pg/mg compared to 22.2 pg/mg for the control group (p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-80559-9