Effect of Fluoride Varnishes on Demineralization and Acid Resistance in Subsurface Demineralized Lesion Models

This study aimed to clarify the effects of high-concentration fluoride varnish application on the inhibition of the progression of initial enamel caries. Remineralization capacity and acid resistance following high-concentration fluoride varnish application were compared with untreated models and mo...

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Bibliographic Details
Published in:Journal of functional biomaterials 2024-12, Vol.15 (12), p.380
Main Authors: Iwawaki, Rika, Horie, Taku, Alhotan, Abdulaziz, Nagatsuka, Yuka, Sakuma, Keiko, Yoshihara, Kumiko, Tsujimoto, Akimasa
Format: Article
Language:English
Subjects:
Acid resistance
Acids
Aluminum
Demineralization
Demineralizing
dental biomaterials
Dental caries
Dental enamel
Electron probe
Electron probes
enamel
fluoride
Fluoride treatments
Fluorides
Microradiography
Mouthwashes
Remineralization
surface analysis
Varnishes
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Summary:This study aimed to clarify the effects of high-concentration fluoride varnish application on the inhibition of the progression of initial enamel caries. Remineralization capacity and acid resistance following high-concentration fluoride varnish application were compared with untreated models and models treated with fluoride mouthwash. Bovine enamel was used to create a model of initial enamel caries. The high-concentration fluoride varnishes Enamelast and Clinpro White Varnish and the fluoride mouthwash Miranol were used. Specimens were evaluated using Contact Microradiography (CMR) and an Electron Probe Micro-Analyzer (EPMA). While a single application of high-concentration fluoride varnish and short-term fluoride mouthwash use did not appear to cause remineralization in the subsurface demineralized layer, improvements in acid resistance were observed, leading to reduced demineralization under subsequent acidic challenges.
ISSN:2079-4983
2079-4983
DOI:10.3390/jfb15120380