Prevalence of Asymptomatic Venous Thromboembolism in Depressive Inpatients

While depression has been recognized as a risk factor for venous thromboembolism (VTE), the prevalence of VTE in depressed inpatients has never been investigated. The aim of this study was thus to examine VTE prevalence and factors associated with VTE in depressed inpatients. We conducted a retrospe...

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Bibliographic Details
Published in:Neuropsychiatric disease and treatment 2020-01, Vol.16, p.579-587
Main Authors: Takeshima, Masahiro, Ishikawa, Hiroyasu, Umeta, Yoshiaki, Kudoh, Mizuki, Umakoshi, Akise, Yoshizawa, Kazuhisa, Ito, Yu, Hosoya, Tomoko, Tsutsui, Ko, Ohta, Hidenobu, Mishima, Kazuo
Format: Article
Language:English
Subjects:
antidepressant
Antidepressants
Antipsychotics
bipolar disorder
Body mass index
Catatonia
depression
Health risk assessment
Medical records
Mental depression
Mental disorders
Original Research
Patients
Psychotropic drugs
Risk factors
Studies
sudden death
Thromboembolism
venous thrombosis
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Summary:While depression has been recognized as a risk factor for venous thromboembolism (VTE), the prevalence of VTE in depressed inpatients has never been investigated. The aim of this study was thus to examine VTE prevalence and factors associated with VTE in depressed inpatients. We conducted a retrospective cross-sectional study of consecutive depressed inpatients (n = 94) from January 1, 2018, to June 30, 2019, at the psychiatry department of Akita University Hospital. As part of our clinical routine, depressed inpatients were screened for VTE using D-dimer, and patients who screened positive underwent enhanced CT to examine VTE. A variety of data was extracted from medical records, including, amongst others, age, sex, body mass index, diagnoses of psychiatric disorders, total scores on the 17-item Hamilton Depression Rating Scale, duration of current depressive episode, daily dosages of antidepressants and antipsychotics, catatonia, and physical restraint. VTE was detected in 8.5% of depressed inpatients. There were no significant differences between VTE-positive and VTE-negative inpatients regarding any of the considered factors. Our analysis shows a VTE prevalence of 8.5% in depressed inpatients, higher than that of 2.3% reported in a previous study in hospitalized patients with psychiatric disorders including depression. This emphasizes the importance of VTE screening for depressive inpatients.
ISSN:1176-6328
1178-2021
1178-2021
DOI:10.2147/NDT.S243308