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Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis

Syphilis is a rare cause of panuveitis. We present the case of a 33-year-old man who presented with diminution of vision of three months duration in his left eye (OS), without any other systemic illness. Ophthalmic examination showed features of pauveitis with dense vitreous exudates, disc pallor an...

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Published in:	Oman journal of ophthalmology 2010-01, Vol.3 (1), p.29-31
Main Authors:	Chhablani, Jay Kumar, Biswas, J, Sudharshan, S
Format:	Article
Language:	English
Subjects:	Care and treatment Case Report Case studies Diagnosis Enzyme-linked immunosorbent assay Eyes & eyesight Health aspects HIV HIV patients Human immunodeficiency virus Medical diagnosis Medical examination ocular syphilis in HIV Ophthalmology Patient outcomes Risk factors Syphilis syphilitic panuveitis in HIV Uveitis
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creator	Chhablani, Jay Kumar Biswas, J Sudharshan, S
description	Syphilis is a rare cause of panuveitis. We present the case of a 33-year-old man who presented with diminution of vision of three months duration in his left eye (OS), without any other systemic illness. Ophthalmic examination showed features of pauveitis with dense vitreous exudates, disc pallor and sheathing of vessels on fundoscopy. A diagnosis of probable endogenous endophthalmitis was made and vitreous tap performed. Vitreous biopsy showed no growth of fungus or bacteria. Rapid plasma reagin (RPR) and Treponema pallidum hemagglutination (TPHA) test were positive. Enzyme-Linked Immuno Sorbent Assay (ELISA) and Western Blot test were then performed, which revealed concurrent HIV infection. The patient improved dramatically with intravenous penicillin therapy. HIV positive patients may present with panuveitis secondary to ocular syphilis, as the only presenting feature in HIV positive patient in absence of any other systemic features.
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We present the case of a 33-year-old man who presented with diminution of vision of three months duration in his left eye (OS), without any other systemic illness. Ophthalmic examination showed features of pauveitis with dense vitreous exudates, disc pallor and sheathing of vessels on fundoscopy. A diagnosis of probable endogenous endophthalmitis was made and vitreous tap performed. Vitreous biopsy showed no growth of fungus or bacteria. Rapid plasma reagin (RPR) and Treponema pallidum hemagglutination (TPHA) test were positive. Enzyme-Linked Immuno Sorbent Assay (ELISA) and Western Blot test were then performed, which revealed concurrent HIV infection. The patient improved dramatically with intravenous penicillin therapy. 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subjects	Care and treatment Case Report Case studies Diagnosis Enzyme-linked immunosorbent assay Eyes & eyesight Health aspects HIV HIV patients Human immunodeficiency virus Medical diagnosis Medical examination ocular syphilis in HIV Ophthalmology Patient outcomes Risk factors Syphilis syphilitic panuveitis in HIV Uveitis
title	Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis
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