Loading…

Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow

The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times in comparison to the batch procedure, while achieving simila...

Full description

Saved in:
Bibliographic Details
Published in:Beilstein journal of organic chemistry 2020-06, Vol.16 (1), p.1305-1312
Main Authors: Nyuchev, Alexander V, Wan, Ting, Cendón, Borja, Sambiagio, Carlo, Struijs, Job J C, Ho, Michelle, Gulías, Moisés, Wang, Ying, Noël, Timothy
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times in comparison to the batch procedure, while achieving similar or higher yields. In addition, the use of inorganic bases was demonstrated to increase the reaction yield under batch conditions.
ISSN:1860-5397
2195-951X
1860-5397
DOI:10.3762/bjoc.16.111