Ultrasound Assessment of Spastic Muscles in Ambulatory Chronic Stroke Survivors Reveals Function-Dependent Changes

• Published in: Journal of rehabilitation medicine 2023-01, Vol.55, p.jrm00342-jrm00342
• Main Authors: González-Buonomo, Javier, Pham, Alexander H, Ghuman, Jaskiran, Malik, Aila, Yozbatiran, Nuray, Francisco, Gerard E, Frontera, Walter R, Li, Sheng
• Format: Article
• Language: English
• Subjects: Age; Aged; Clinical assessment; Evaluation; Female; function; Grip strength; Humans; Limbs; Middle Aged; Muscle Spasticity - diagnostic imaging; Muscle Spasticity - etiology; Muscle, Skeletal - diagnostic imaging; Muscles; Original Report; Postural Balance; Spasticity; Stroke; Stroke - diagnostic imaging; Stroke Rehabilitation; Survivor; Survivors; Time and Motion Studies; Ultrasonic imaging; Ultrasonography; ultrasound
• ISSN: 1651-2081; 1650-1977; 1651-2081
• DOI: 10.2340/jrm.v54.3199

To correlate ultrasound characteristics of spastic muscles with clinical and functional measurements in chronic stroke survivors. Ultrasound assessment and clinical and functional assessments were performed in 28 ambulatory stroke survivors (12 females, mean age 57.8 ± 11.8 years, 76 ± 45 months after stroke). Muscle thickness in the affected side was decreased compared with the contralateral side (p < 0.001). The decrease was more evident in the upper limb muscles. On the affected side, the modified Heckmatt scale score was lowest (closer to normal) in the rectus femoris (RF) muscle compared with other muscles (biceps brachii (BB), flexor carpi ulnaris (FCU) and medial gastrocnemius (MG)). Muscle thickness and echogenicity of spastic muscles did not correlate with spasticity, as measured with the modified Ashworth scale (MAS), Fugl-Meyer motor assessment scores, age, or time since stroke. There was a significant negative correlation between grip strength and percentage decrease in muscle thickness for the spastic FCU muscle (r = -0.49, p = 0.008). RF muscle thickness correlated with ambulatory function (Timed Up and Go test (r = 0.44, p = 0.021) and 6-metre walk test (r = 0.41, p = 0.032)). There was no significant correlation between echogenicity and functional assessments Conclusion: Ambulatory chronic stroke survivors had function-dependent changes in muscle thickness on the affected side. Muscle thickness and echogenicity of spastic muscles did not correlate with spasticity, Fugl-Meyer motor assessment scores, age, or time since stroke.