Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography

• Published in: BMC medical imaging 2023-11, Vol.23 (1), p.194-194, Article 194
• Main Authors: Ni, Hailong, Xu, Suzhong, Tian, Li, Mao, Jieli, Li, Jing, Lin, Na, Hu, Peike, Wu, Zhiyi, Chen, Xiang, Bao, Zhishu, Zheng, Jingwei, Yan, Peihua, Deng, Ruzhi
• Format: Article
• Language: English
• Subjects: Agreement; Agreements; AOCT-1000 M; Axial length; Cataracts; Central corneal thickness; Clinical significance; Comparative analysis; Confidence intervals; Cornea; Cornea - diagnostic imaging; Correlation coefficient; Correlation coefficients; Eye surgery; Humans; Hypotheses; Interferometry; Lasers in medicine; Mapping; Measurement; Measuring instruments; Medical technology; Morphology; Myopia; Optical Coherence Tomography; Repeatability; Reproducibility; Reproducibility of Results; RTVue XR; Software; Statistical analysis; Thickness measurement; Tomography; Tomography, Optical Coherence - methods
• ISSN: 1471-2342; 1471-2342
• DOI: 10.1186/s12880-023-01147-7

To evaluate the repeatability and agreement of Fourier-domain optical coherence tomography (AOCT-1000 M and RTVue XR) and partial coherence interferometry biometer (IOL Master 500) in measuring corneal thickness mapping and axial length respectively. Corneal thickness was measured by AOCT-1000 M and RTVue XR. Axial lengths were measured by AOCT-1000 M and IOL Master 500. The repeatability and agreement of corneal thickness and axial length were calculated in two groups of devices. The intraclass correlation coefficient (ICC) was used to verify the repeatability of the device. The 95% confidence interval of the difference compared to the set cut-off value was used to verify the agreement between the two devices. A total of 60 subjects with 58 eyes were included. The central corneal thickness measured by AOCT-1000 M and RTVue XR were 504.46 ± 42.53 μm and 504.43 ± 42.89 μm respectively. The average difference between groups was 0.03 ± 4.58 μm, and the 95% confidence interval was (-1.17, 1.24), which was far less than the set threshold value of 15 μm (P