Advocating the Use of Loop-mediated Isothermal Amplification Assay to Improve the Rates of Diagnosis of Pulmonary Tuberculosis in Resource-constraint Settings

Tuberculosis (TB) continues to remain one of the top infectious diseases on a global scale. Acknowledging the gains observed, specific targets have been set as a part of the Sustainable Development Goals, and global leaders are hoping for significant improvement by 2030. In order to achieve this goa...

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Bibliographic Details
Published in:Indian journal of respiratory care 2023-06, Vol.12 (2), p.199-200
Main Authors: Shrivastava, Saurabh RamBihariLal, Shrivastava, Prateek S
Format: Article
Language:English
Subjects:
loop-mediated isothermal amplification
tuberculosis
world health organization
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Summary:Tuberculosis (TB) continues to remain one of the top infectious diseases on a global scale. Acknowledging the gains observed, specific targets have been set as a part of the Sustainable Development Goals, and global leaders are hoping for significant improvement by 2030. In order to achieve this goal, an end TB strategy has been proposed, and great emphasis has been given toward enhancing case detection. Realizing the need, the World Health Organization (WHO) has given more attention toward the development and evaluation of new diagnostic tools and drug susceptibility testing. A molecular assay based on loop-mediated isothermal amplification (LAMP) has been developed to promote the detection of the Mycobacterium tuberculosis (M. tb) TB complex. This test can be easily performed at a peripheral level, requires minimal laboratory infrastructure and limited biosafety standards, is easy to use, and results are available in
ISSN:2277-9019
2321-4899
DOI:10.5005/jp-journals-11010-1037