Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research

Each year the American Thoracic Society (ATS) Conference brings together scientists who conduct basic, translational and clinical research to present on the recent advances in the field of respirology. Due to the Coronavirus Disease of 2019 (COVID-19) pandemic, the ATS2020 Conference was held online...

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Bibliographic Details
Published in:Pulmonary Circulation 2021-07, Vol.11 (3), p.1-13
Main Authors: Potus, Francois, Frump, Andrea L., Umar, Soban, R. Vanderpool, Rebecca, Al Ghouleh, Imad, Lai, Yen-Chun
Format: Article
Language:English
Subjects:
ATS
basic science research
Coronaviruses
COVID-19
Medical research
Pulmonary hypertension
Review
Translational research
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Summary:Each year the American Thoracic Society (ATS) Conference brings together scientists who conduct basic, translational and clinical research to present on the recent advances in the field of respirology. Due to the Coronavirus Disease of 2019 (COVID-19) pandemic, the ATS2020 Conference was held online in a series of virtual meetings. In this review, we focus on the breakthroughs in pulmonary hypertension research. We have selected 11 of the best basic science abstracts which were presented at the ATS2020 Assembly on Pulmonary Circulation mini-symposium “What’s New in Pulmonary Arterial Hypertension (PAH) and Right Ventricular (RV) Signaling: Lessons from the Best Abstracts,” reflecting the current state of the art and associated challenges in PH. Particular emphasis is placed on understanding the mechanisms underlying RV failure, the regulation of inflammation, and the novel therapeutic targets that emerged from preclinical research. The pathologic interactions between pulmonary hypertension, right ventricular function and COVID-19 are also discussed.
ISSN:2045-8940
2045-8932
2045-8940
DOI:10.1177/20458940211037274