Loading…

Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research

Each year the American Thoracic Society (ATS) Conference brings together scientists who conduct basic, translational and clinical research to present on the recent advances in the field of respirology. Due to the Coronavirus Disease of 2019 (COVID-19) pandemic, the ATS2020 Conference was held online...

Full description

Saved in:
Bibliographic Details
Published in:Pulmonary Circulation 2021-07, Vol.11 (3), p.1-13
Main Authors: Potus, Francois, Frump, Andrea L., Umar, Soban, R. Vanderpool, Rebecca, Al Ghouleh, Imad, Lai, Yen-Chun
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c5359-2a6992c19fa6bde948b0f62277ffc731b2fe84d44edd3b2ade95c5881a1c7f4d3
container_end_page 13
container_issue 3
container_start_page 1
container_title Pulmonary Circulation
container_volume 11
creator Potus, Francois
Frump, Andrea L.
Umar, Soban
R. Vanderpool, Rebecca
Al Ghouleh, Imad
Lai, Yen-Chun
description Each year the American Thoracic Society (ATS) Conference brings together scientists who conduct basic, translational and clinical research to present on the recent advances in the field of respirology. Due to the Coronavirus Disease of 2019 (COVID-19) pandemic, the ATS2020 Conference was held online in a series of virtual meetings. In this review, we focus on the breakthroughs in pulmonary hypertension research. We have selected 11 of the best basic science abstracts which were presented at the ATS2020 Assembly on Pulmonary Circulation mini-symposium “What’s New in Pulmonary Arterial Hypertension (PAH) and Right Ventricular (RV) Signaling: Lessons from the Best Abstracts,” reflecting the current state of the art and associated challenges in PH. Particular emphasis is placed on understanding the mechanisms underlying RV failure, the regulation of inflammation, and the novel therapeutic targets that emerged from preclinical research. The pathologic interactions between pulmonary hypertension, right ventricular function and COVID-19 are also discussed.
doi_str_mv 10.1177/20458940211037274
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_6a79414d30d94257aea5cdc580bdb63f</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_20458940211037274</sage_id><doaj_id>oai_doaj_org_article_6a79414d30d94257aea5cdc580bdb63f</doaj_id><sourcerecordid>2568200374</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5359-2a6992c19fa6bde948b0f62277ffc731b2fe84d44edd3b2ade95c5881a1c7f4d3</originalsourceid><addsrcrecordid>eNqFks9uEzEQxlcIRKvSB-CCLHHhkmJ7vX_cA1IJFCJFKoKWq-W1xxtHm3Vq76bq8_CiTJoSWhBiLx6Pv-_nGe9k2UtGTxirqreciqKWgnLGaF7xSjzJDre5yTb59EF8kB2ntKT4Cck4rZ9nB7kQuShEfpj9-AoG-oFou9G9gRXGifierMduFXodb4mOA0SvO7K4XQPGffKhJ7q3JPp2MZAFoII47bsxAomQcG8WpyRsIG483JDgSIIOzACW6CYNURu8w8WwImeX3zjl9I6Gd8fW9y2ZXnyffZgwuWe9yJ453SU4vl-Psqvzj5fTz5P5xafZ9Gw-MUVeyAnXpZTcMOl02ViQom6oKzmvKudMlbOGO6iFFQKszRuuUVKYoq6ZZqZywuZH2WzHtUEv1Tr6FfavgvbqLhFiq7BVbzpQpa6kYOihVgpeVBp0YSzSaGObMnfIerdjrcdmBXb7xlF3j6CPT3q_UG3YqDqvGf4dBLy5B8RwPUIa1MonA12newhjUrwohRQVkyVKX_8hXYYx9vhUW1XNKc6HQBXbqUwMKUVw-2IYVduJUn9NFHpePexi7_g1Pyg43QlufAe3_yeqL1dz_v4cZ1FKNJ_szEm38Lvmf5fzE2IX5dQ</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2568200374</pqid></control><display><type>article</type><title>Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research</title><source>Publicly Available Content Database</source><source>Wiley Open Access Journals</source><source>PubMed Central</source><source>Coronavirus Research Database</source><creator>Potus, Francois ; Frump, Andrea L. ; Umar, Soban ; R. Vanderpool, Rebecca ; Al Ghouleh, Imad ; Lai, Yen-Chun</creator><creatorcontrib>Potus, Francois ; Frump, Andrea L. ; Umar, Soban ; R. Vanderpool, Rebecca ; Al Ghouleh, Imad ; Lai, Yen-Chun ; ATS Pulmonary Circulation Early Career Working Group</creatorcontrib><description>Each year the American Thoracic Society (ATS) Conference brings together scientists who conduct basic, translational and clinical research to present on the recent advances in the field of respirology. Due to the Coronavirus Disease of 2019 (COVID-19) pandemic, the ATS2020 Conference was held online in a series of virtual meetings. In this review, we focus on the breakthroughs in pulmonary hypertension research. We have selected 11 of the best basic science abstracts which were presented at the ATS2020 Assembly on Pulmonary Circulation mini-symposium “What’s New in Pulmonary Arterial Hypertension (PAH) and Right Ventricular (RV) Signaling: Lessons from the Best Abstracts,” reflecting the current state of the art and associated challenges in PH. Particular emphasis is placed on understanding the mechanisms underlying RV failure, the regulation of inflammation, and the novel therapeutic targets that emerged from preclinical research. The pathologic interactions between pulmonary hypertension, right ventricular function and COVID-19 are also discussed.</description><identifier>ISSN: 2045-8940</identifier><identifier>ISSN: 2045-8932</identifier><identifier>EISSN: 2045-8940</identifier><identifier>DOI: 10.1177/20458940211037274</identifier><identifier>PMID: 34434543</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>ATS ; basic science research ; Coronaviruses ; COVID-19 ; Medical research ; Pulmonary hypertension ; Review ; Translational research</subject><ispartof>Pulmonary Circulation, 2021-07, Vol.11 (3), p.1-13</ispartof><rights>The Author(s) 2021</rights><rights>The Author(s)</rights><rights>The Author(s) 2021.</rights><rights>The Author(s) 2021. This work is licensed under the Creative Commons Attribution – Non-Commercial License https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2021 2021 SAGE Publications Ltd, or Pulmonary Vascular Research Institute, unless otherwise noted. Manuscript content on this site is licensed under Creative Commons Licenses</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c5359-2a6992c19fa6bde948b0f62277ffc731b2fe84d44edd3b2ade95c5881a1c7f4d3</cites><orcidid>0000-0001-8036-3079 ; 0000-0002-4703-5708</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381443/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2568200374?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,313,314,727,780,784,792,885,11562,25753,27922,27924,27925,37012,37013,38516,43895,44590,46052,46476,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34434543$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Potus, Francois</creatorcontrib><creatorcontrib>Frump, Andrea L.</creatorcontrib><creatorcontrib>Umar, Soban</creatorcontrib><creatorcontrib>R. Vanderpool, Rebecca</creatorcontrib><creatorcontrib>Al Ghouleh, Imad</creatorcontrib><creatorcontrib>Lai, Yen-Chun</creatorcontrib><creatorcontrib>ATS Pulmonary Circulation Early Career Working Group</creatorcontrib><title>Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research</title><title>Pulmonary Circulation</title><addtitle>Pulm Circ</addtitle><description>Each year the American Thoracic Society (ATS) Conference brings together scientists who conduct basic, translational and clinical research to present on the recent advances in the field of respirology. Due to the Coronavirus Disease of 2019 (COVID-19) pandemic, the ATS2020 Conference was held online in a series of virtual meetings. In this review, we focus on the breakthroughs in pulmonary hypertension research. We have selected 11 of the best basic science abstracts which were presented at the ATS2020 Assembly on Pulmonary Circulation mini-symposium “What’s New in Pulmonary Arterial Hypertension (PAH) and Right Ventricular (RV) Signaling: Lessons from the Best Abstracts,” reflecting the current state of the art and associated challenges in PH. Particular emphasis is placed on understanding the mechanisms underlying RV failure, the regulation of inflammation, and the novel therapeutic targets that emerged from preclinical research. The pathologic interactions between pulmonary hypertension, right ventricular function and COVID-19 are also discussed.</description><subject>ATS</subject><subject>basic science research</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Medical research</subject><subject>Pulmonary hypertension</subject><subject>Review</subject><subject>Translational research</subject><issn>2045-8940</issn><issn>2045-8932</issn><issn>2045-8940</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>AFRWT</sourceid><sourceid>24P</sourceid><sourceid>COVID</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqFks9uEzEQxlcIRKvSB-CCLHHhkmJ7vX_cA1IJFCJFKoKWq-W1xxtHm3Vq76bq8_CiTJoSWhBiLx6Pv-_nGe9k2UtGTxirqreciqKWgnLGaF7xSjzJDre5yTb59EF8kB2ntKT4Cck4rZ9nB7kQuShEfpj9-AoG-oFou9G9gRXGifierMduFXodb4mOA0SvO7K4XQPGffKhJ7q3JPp2MZAFoII47bsxAomQcG8WpyRsIG483JDgSIIOzACW6CYNURu8w8WwImeX3zjl9I6Gd8fW9y2ZXnyffZgwuWe9yJ453SU4vl-Psqvzj5fTz5P5xafZ9Gw-MUVeyAnXpZTcMOl02ViQom6oKzmvKudMlbOGO6iFFQKszRuuUVKYoq6ZZqZywuZH2WzHtUEv1Tr6FfavgvbqLhFiq7BVbzpQpa6kYOihVgpeVBp0YSzSaGObMnfIerdjrcdmBXb7xlF3j6CPT3q_UG3YqDqvGf4dBLy5B8RwPUIa1MonA12newhjUrwohRQVkyVKX_8hXYYx9vhUW1XNKc6HQBXbqUwMKUVw-2IYVduJUn9NFHpePexi7_g1Pyg43QlufAe3_yeqL1dz_v4cZ1FKNJ_szEm38Lvmf5fzE2IX5dQ</recordid><startdate>202107</startdate><enddate>202107</enddate><creator>Potus, Francois</creator><creator>Frump, Andrea L.</creator><creator>Umar, Soban</creator><creator>R. Vanderpool, Rebecca</creator><creator>Al Ghouleh, Imad</creator><creator>Lai, Yen-Chun</creator><general>SAGE Publications</general><general>John Wiley &amp; Sons, Inc</general><general>Wiley</general><scope>AFRWT</scope><scope>24P</scope><scope>WIN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-8036-3079</orcidid><orcidid>https://orcid.org/0000-0002-4703-5708</orcidid></search><sort><creationdate>202107</creationdate><title>Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research</title><author>Potus, Francois ; Frump, Andrea L. ; Umar, Soban ; R. Vanderpool, Rebecca ; Al Ghouleh, Imad ; Lai, Yen-Chun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5359-2a6992c19fa6bde948b0f62277ffc731b2fe84d44edd3b2ade95c5881a1c7f4d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>ATS</topic><topic>basic science research</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Medical research</topic><topic>Pulmonary hypertension</topic><topic>Review</topic><topic>Translational research</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Potus, Francois</creatorcontrib><creatorcontrib>Frump, Andrea L.</creatorcontrib><creatorcontrib>Umar, Soban</creatorcontrib><creatorcontrib>R. Vanderpool, Rebecca</creatorcontrib><creatorcontrib>Al Ghouleh, Imad</creatorcontrib><creatorcontrib>Lai, Yen-Chun</creatorcontrib><creatorcontrib>ATS Pulmonary Circulation Early Career Working Group</creatorcontrib><collection>SAGE Open Access</collection><collection>Wiley Open Access Journals</collection><collection>Wiley Online Library Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Pulmonary Circulation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Potus, Francois</au><au>Frump, Andrea L.</au><au>Umar, Soban</au><au>R. Vanderpool, Rebecca</au><au>Al Ghouleh, Imad</au><au>Lai, Yen-Chun</au><aucorp>ATS Pulmonary Circulation Early Career Working Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research</atitle><jtitle>Pulmonary Circulation</jtitle><addtitle>Pulm Circ</addtitle><date>2021-07</date><risdate>2021</risdate><volume>11</volume><issue>3</issue><spage>1</spage><epage>13</epage><pages>1-13</pages><issn>2045-8940</issn><issn>2045-8932</issn><eissn>2045-8940</eissn><abstract>Each year the American Thoracic Society (ATS) Conference brings together scientists who conduct basic, translational and clinical research to present on the recent advances in the field of respirology. Due to the Coronavirus Disease of 2019 (COVID-19) pandemic, the ATS2020 Conference was held online in a series of virtual meetings. In this review, we focus on the breakthroughs in pulmonary hypertension research. We have selected 11 of the best basic science abstracts which were presented at the ATS2020 Assembly on Pulmonary Circulation mini-symposium “What’s New in Pulmonary Arterial Hypertension (PAH) and Right Ventricular (RV) Signaling: Lessons from the Best Abstracts,” reflecting the current state of the art and associated challenges in PH. Particular emphasis is placed on understanding the mechanisms underlying RV failure, the regulation of inflammation, and the novel therapeutic targets that emerged from preclinical research. The pathologic interactions between pulmonary hypertension, right ventricular function and COVID-19 are also discussed.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>34434543</pmid><doi>10.1177/20458940211037274</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0001-8036-3079</orcidid><orcidid>https://orcid.org/0000-0002-4703-5708</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2045-8940
ispartof Pulmonary Circulation, 2021-07, Vol.11 (3), p.1-13
issn 2045-8940
2045-8932
2045-8940
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_6a79414d30d94257aea5cdc580bdb63f
source Publicly Available Content Database; Wiley Open Access Journals; PubMed Central; Coronavirus Research Database
subjects ATS
basic science research
Coronaviruses
COVID-19
Medical research
Pulmonary hypertension
Review
Translational research
title Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T19%3A44%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Recent%20advancements%20in%20pulmonary%20arterial%20hypertension%20and%20right%20heart%20failure%20research:%20overview%20of%20selected%20abstracts%20from%20ATS2020%20and%20emerging%20COVID-19%20research&rft.jtitle=Pulmonary%20Circulation&rft.au=Potus,%20Francois&rft.aucorp=ATS%20Pulmonary%20Circulation%20Early%20Career%20Working%20Group&rft.date=2021-07&rft.volume=11&rft.issue=3&rft.spage=1&rft.epage=13&rft.pages=1-13&rft.issn=2045-8940&rft.eissn=2045-8940&rft_id=info:doi/10.1177/20458940211037274&rft_dat=%3Cproquest_doaj_%3E2568200374%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5359-2a6992c19fa6bde948b0f62277ffc731b2fe84d44edd3b2ade95c5881a1c7f4d3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2568200374&rft_id=info:pmid/34434543&rft_sage_id=10.1177_20458940211037274&rfr_iscdi=true