CD4 and CD20 as important immune markers in patients with pulmonary tuberculosis

Tuberculosis (TB) is a serious lung infection caused by the bacterium Mycobacterium tuberculosis ( M. tuberculosis ) is highly contagious, and can be spread through the air from an infected person to others. The aim of this article was to evaluate the immunological role of CD4 and CD20 in patients i...

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Bibliographic Details
Published in:E3S web of conferences 2023-01, Vol.389, p.3108
Main Authors: Kamoona, Firas Mohammad Hussein, Aljanaby, Ahmed Abduljabbar Jaloob
Format: Article
Language:English
Subjects:
cd20
cd4
genexpert
mdrmtb
mtb
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Summary:Tuberculosis (TB) is a serious lung infection caused by the bacterium Mycobacterium tuberculosis ( M. tuberculosis ) is highly contagious, and can be spread through the air from an infected person to others. The aim of this article was to evaluate the immunological role of CD4 and CD20 in patients infected with M. tuberculosis and multi-drug resistant tuberculosis (MDRTB). A total of 182 individuals suspected with M. tuberculosis admitted to the tuberculosis center in AL-Najaf City, Iraq. A sputum acid-fast stain was performed for each individual and GeneXpert® heminested real time PCR has been performed for MDR- M. tuberculosis detection. CD4 and CD20 have been measurement in serum of infected individual using ELISA technique. Serum CD4 and CD20 levels were significantly elevated (P
ISSN:2267-1242
2267-1242
DOI:10.1051/e3sconf/202338903108