Hepatobiliary and Gastrointestinal Involvement in Langerhans Cell Histiocytosis—Spectrum of Three Cases

Abstract Langerhans cell histiocytosis (LCH) is a rare group of disorder, due to clonal neoplastic proliferation of dendritic cells in the bone marrow expressing a Langerhans cell phenotype.1 This disease particularly affects the pediatric age group and young adults and often presents with skin rash...

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Bibliographic Details
Published in:The Indian journal of radiology & imaging 2021-07, Vol.31 (3), p.670-677
Main Authors: Pratap, Thara, Jalal, Muhammed Jasim Abdul, R., Rashmi, Gopalakrishnabhakthan, Anupama, AK, Vishnu
Format: Article
Language:English
Subjects:
alanine aminotransferase
gastrointestinal
histiocytosis
langerhans cell
nodular
Pictorial
Pictorial Essay
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Summary:Abstract Langerhans cell histiocytosis (LCH) is a rare group of disorder, due to clonal neoplastic proliferation of dendritic cells in the bone marrow expressing a Langerhans cell phenotype.1 This disease particularly affects the pediatric age group and young adults and often presents with skin rashes, lung infiltrates, and bone lesions. It can also manifest with endocrine dysfunction and hematopoietic disorders. Involvement of gastrointestinal tract is very rare. Herein, we present a spectrum of three cases with gastrointestinal involvement.
ISSN:0971-3026
1998-3808
DOI:10.1055/s-0041-1735505