Decreased Iron Ion Concentrations in the Peripheral Blood Correlate with Coronary Atherosclerosis

(1) Background: Obesity and diabetes continue to reach epidemic levels in the population with major health impacts that include a significantly increased risk of coronary atherosclerosis. The imbalance of trace elements in the body caused by nutritional factors can lead to the progression of coronar...

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Published in:Nutrients 2022-01, Vol.14 (2), p.319
Main Authors: Meng, Heyu, Wang, Yueying, Ruan, Jianjun, Chen, Yanqiu, Wang, Xue, Zhou, Fengfeng, Meng, Fanbo
Format: Article
Language:English
Subjects:
Acute Disease
acute myocardial infarction
Aged
Arteriosclerosis
Atherosclerosis
Blood
Body mass index
Calcium
Calcium - blood
Cardiovascular disease
Cardiovascular diseases
Colorimetry
Coronary artery
Coronary artery disease
Coronary Artery Disease - blood
Coronary Artery Disease - complications
coronary atherosclerosis
Diabetes mellitus
Epidemics
Female
Heart diseases
Humans
Ions
Iron
Iron - blood
Iron Deficiencies - blood
Iron Deficiencies - complications
iron ions
Magnesium
Magnesium - blood
Male
Middle Aged
Mortality
Myocardial infarction
Myocardial Infarction - blood
Myocardial Infarction - complications
Obesity
Patients
Peripheral blood
Potassium
Potassium - blood
Quality assessment
Quality control
Samples
Sodium
Sodium - blood
stable coronary artery disease
Statistical analysis
Statistical methods
Statistics
Trace elements
Trace Elements - blood
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Summary:(1) Background: Obesity and diabetes continue to reach epidemic levels in the population with major health impacts that include a significantly increased risk of coronary atherosclerosis. The imbalance of trace elements in the body caused by nutritional factors can lead to the progression of coronary atherosclerosis. (2) Methods: We measured the concentrations of sodium (Na), potassium (K), magnesium (Mg), calcium (Ca), Zinc (Zn), and iron (Fe) in peripheral blood samples from 4243 patients and performed baseline analysis and propensity matching of the patient datasets. The patients were grouped into acute myocardial infarction (AMI, 702 patients) and stable coronary heart disease (SCAD1, 253 patients) groups. Both of these groups were included in the AS that had a total of 1955 patients. The control group consisted of 2288 patients. The plasma concentrations of calcium, magnesium, and iron were measured using a colorimetric method. For comparison, 15 external quality assessment (EQA) samples were selected from the Clinical Laboratory Center of the Ministry of Health of China. SPSS software was used for statistical analysis. The average values and deviations of all of the indicators in each group were calculated, and a -value threshold of
ISSN:2072-6643
2072-6643
DOI:10.3390/nu14020319