Treatment and Management of Acinetobacter Pneumonia: Lessons Learned from Recent World Event

• Published in: Infection and drug resistance 2024-01, Vol.17, p.507-529
• Main Authors: Rangel, Karyne, De-Simone, Salvatore Giovanni
• Format: Article
• Language: English
• Subjects: acinetobacter baumannii; carbapenem-resistant a. baumannii; covid-19; crab; hap; hospital-acquired pneumonia; pneumonia; Review; vap; ventilator-associated pneumonia
• ISSN: 1178-6973; 1178-6973
• DOI: 10.2147/IDR.S431525

pneumonia is a significant healthcare-associated infection that poses a considerable challenge to clinicians due to its multidrug-resistant nature. Recent world events, such as the COVID-19 pandemic, have highlighted the need for effective treatment and management strategies for Acinetobacter pneumonia. In this review, we discuss lessons learned from recent world events, particularly the COVID-19 pandemic, in the context of the treatment and management of pneumonia. We performed an extensive literature review to uncover studies and information pertinent to the topic. The COVID-19 pandemic underscored the importance of infection control measures in healthcare settings, including proper hand hygiene, isolation protocols, and personal protective equipment use, to prevent the spread of multidrug-resistant pathogens like . Additionally, the pandemic highlighted the crucial role of antimicrobial stewardship programs in optimizing antibiotic use and curbing the emergence of resistance. Advances in diagnostic techniques, such as rapid molecular testing, have also proven valuable in identifying infections promptly. Furthermore, due to the limited availability of antibiotics for treating infections caused , alternative strategies are needed like the use of antimicrobial peptides, bacteriophages and their enzymes, nanoparticles, photodynamic and chelate therapy. Recent world events, particularly the COVID-19 pandemic, have provided valuable insights into the treatment and management of pneumonia. These lessons emphasize the significance of infection control, antimicrobial stewardship, and early diagnostics in combating this challenging infection.