Surgical Management for Transposed Ovarian Recurrence of Cervical Cancer: A Systematic Review with Our Experience

In early-stage cervical cancer, ovarian metastasis is relatively rare, and ovarian transposition is often performed during surgery. Although rare, the diagnosis and surgical approach for recurrence at transposed ovaries are challenging. This study focused on the diagnosis and surgical management of...

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Bibliographic Details
Published in:Current oncology (Toronto) 2022-09, Vol.29 (10), p.7158-7170
Main Authors: Maeda, Michihide, Hisa, Tsuyoshi, Kurahashi, Hiroki, Hayashida, Harue, Lee, Misooja, Kakubari, Reisa, Matsuzaki, Shinya, Mabuchi, Seiji, Kamiura, Shoji
Format: Article
Language:English
Subjects:
Cancer
Cervical cancer
Diseases
Female
Health aspects
Humans
Hysterectomy
laparoscopic resection
Menopause
Metastasis
Middle Aged
Oncology, Experimental
ovarian metastasis
Ovarian Neoplasms - surgery
ovarian transposition
Pelvis
PET imaging
Relapse
Systematic Review
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - surgery
Women
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Summary:In early-stage cervical cancer, ovarian metastasis is relatively rare, and ovarian transposition is often performed during surgery. Although rare, the diagnosis and surgical approach for recurrence at transposed ovaries are challenging. This study focused on the diagnosis and surgical management of transposed ovarian recurrence in cervical cancer patients. A 45-year-old premenopausal woman underwent radical hysterectomy, bilateral salpingectomy, and pelvic lymphadenectomy following postoperative concurrent chemoradiotherapy for stage IB1 cervical cancer. During the initial surgery, the ovary was transposed to the paracolic gutter, and no postoperative complications were observed. Ovarian recurrence was diagnosed using positron emission tomography-computed tomography, and a laparoscopic bilateral oophorectomy was performed. A systematic review identified nine women with transposed ovarian recurrence with no other metastases of cervical cancer, and no studies have discussed the optimal surveillance of transposed ovaries. Of those (n = 9), four women had died of the disease within 2 years of the second surgery, and the prognosis of transposed ovarian cervical cancer seemed poor. Nevertheless, three women underwent laparoscopic oophorectomies, none of whom experienced recurrence after the second surgery. Few studies have examined the surgical management of transposed ovarian recurrence. The optimal surgical approach for transposed ovarian recurrence of cervical cancer requires further investigation.
ISSN:1718-7729
1198-0052
1718-7729
DOI:10.3390/curroncol29100563