Monitoring effectiveness of programmes to prevent mother-to-child HIV transmission in lower-income countries

Ambitious goals for paediatric AIDS control have been set by various international bodies, including a 50% reduction in new paediatric infections by 2010. While these goals are clearly appropriate in their scope, the lack of clarity and consensus around how to monitor the effectiveness of programmes...

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Published in:Bulletin of the World Health Organization 2008-01, Vol.86 (1), p.57-62
Main Authors: Stringer, Elizabeth M, Chi, Benjamin H, Chintu, Namwinga, Creek, Tracy L, Ekouevi, Didier K, Coetzee, David, Tih, Pius, Boulle, Andrew, Dabis, Francois, Shaffer, Nathan, Wilfert, Catherine M, Stringer, Jeffrey S A
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Breastfeeding & lactation
Child health
Clinical trials
Communicable diseases
Developing Countries
Disease prevention
Disease transmission
Female
Health policy
Health Surveys
HIV
HIV Infections
HIV Infections - mortality
HIV Infections - prevention & control
HIV Infections - transmission
Human immunodeficiency virus
Humans
Infant, Newborn
Infectious Disease Transmission, Vertical
Infectious Disease Transmission, Vertical - prevention & control
Infectious Disease Transmission, Vertical - statistics & numerical data
Intervention
Laboratories
LDCs
Life Sciences
Maternal and infant welfare
Medical tests
Mothers
Organizational Objectives
Pediatrics
Policy and Practice
Population
Pregnancy
Pregnancy Complications, Infectious
Pregnancy Complications, Infectious - prevention & control
Prevention
Program Evaluation
Program Evaluation - methods
Public health
Santé publique et épidémiologie
Surveillance
Survival Rate
Womens health
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container_end_page 62
container_issue 1
container_start_page 57
container_title Bulletin of the World Health Organization
container_volume 86
creator Stringer, Elizabeth M
Chi, Benjamin H
Chintu, Namwinga
Creek, Tracy L
Ekouevi, Didier K
Coetzee, David
Tih, Pius
Boulle, Andrew
Dabis, Francois
Shaffer, Nathan
Wilfert, Catherine M
Stringer, Jeffrey S A
description Ambitious goals for paediatric AIDS control have been set by various international bodies, including a 50% reduction in new paediatric infections by 2010. While these goals are clearly appropriate in their scope, the lack of clarity and consensus around how to monitor the effectiveness of programmes to prevent mother-to-child HIV transmission (PMTCT) makes it difficult for policy-makers to mount a coordinated response. In this paper, we develop the case for using population HIV-free child survival as a gold standard metric to measure the effectiveness of PMTCT programmes, and go on to consider multiple study designs and source populations. Finally, we propose a novel community survey-based approach that could be implemented widely throughout the developing world with minor modifications to ongoing Demographic and Health Surveys.
doi_str_mv 10.2471/BLT.07.043117
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source International Bibliography of the Social Sciences (IBSS); Open Access: PubMed Central; ABI/INFORM global; Social Science Premium Collection; Politics Collection; PAIS Index
subjects Acquired immune deficiency syndrome
AIDS
Breastfeeding & lactation
Child health
Clinical trials
Communicable diseases
Developing Countries
Disease prevention
Disease transmission
Female
Health policy
Health Surveys
HIV
HIV Infections
HIV Infections - mortality
HIV Infections - prevention & control
HIV Infections - transmission
Human immunodeficiency virus
Humans
Infant, Newborn
Infectious Disease Transmission, Vertical
Infectious Disease Transmission, Vertical - prevention & control
Infectious Disease Transmission, Vertical - statistics & numerical data
Intervention
Laboratories
LDCs
Life Sciences
Maternal and infant welfare
Medical tests
Mothers
Organizational Objectives
Pediatrics
Policy and Practice
Population
Pregnancy
Pregnancy Complications, Infectious
Pregnancy Complications, Infectious - prevention & control
Prevention
Program Evaluation
Program Evaluation - methods
Public health
Santé publique et épidémiologie
Surveillance
Survival Rate
Womens health
title Monitoring effectiveness of programmes to prevent mother-to-child HIV transmission in lower-income countries
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