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Phytochemicals in Gynecological Cancer Prevention

Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhib...

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Published in:International journal of molecular sciences 2021-01, Vol.22 (3), p.1219
Main Authors: Woźniak, Marta, Krajewski, Rafał, Makuch, Sebastian, Agrawal, Siddarth
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description Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhibiting the early stages of carcinogenesis or improving the efficacy of traditional chemotherapeutic agents. Moreover, a number of epidemiological studies have investigated associations between a plant-based diet and cancer risk. This literature review summarizes the current knowledge on the phytochemicals with proven antitumor activity, emphasizing their effectiveness and mechanism of action in gynecological cancer.
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subjects Acids
Animals
anticancer
Antitumor activity
Carcinogenesis
Carcinogens
Carotenoids
Cervical cancer
Cervix
Chemoprevention - methods
Chemotherapy
Diet
Disease prevention
Endometrial cancer
Endometrium
Epidemiology
Female
Flavonoids
Fruits
Genital Neoplasms, Female - drug therapy
Genital Neoplasms, Female - prevention & control
Gynecological cancer
gynecological cancers
Gynecology
Human papillomavirus
Humans
Infections
Literature reviews
Medical screening
Ovarian cancer
Phytochemicals
Phytochemicals - chemistry
Phytochemicals - classification
Phytochemicals - pharmacology
Phytochemicals - therapeutic use
Plants
Polyphenols
Polyphenols - chemistry
Polyphenols - pharmacology
Polyphenols - therapeutic use
Review
Structure-Activity Relationship
Sulfhydryl Compounds - chemistry
Sulfhydryl Compounds - pharmacology
Sulfhydryl Compounds - therapeutic use
Terpenes - chemistry
Terpenes - pharmacology
Terpenes - therapeutic use
Tumors
Womens health
title Phytochemicals in Gynecological Cancer Prevention
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