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Phytochemicals in Gynecological Cancer Prevention
Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhib...
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Published in: | International journal of molecular sciences 2021-01, Vol.22 (3), p.1219 |
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creator | Woźniak, Marta Krajewski, Rafał Makuch, Sebastian Agrawal, Siddarth |
description | Gynecological cancer confers an enormous burden among women worldwide. Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhibiting the early stages of carcinogenesis or improving the efficacy of traditional chemotherapeutic agents. Moreover, a number of epidemiological studies have investigated associations between a plant-based diet and cancer risk. This literature review summarizes the current knowledge on the phytochemicals with proven antitumor activity, emphasizing their effectiveness and mechanism of action in gynecological cancer. |
doi_str_mv | 10.3390/ijms22031219 |
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Accumulating evidence points to the role of phytochemicals in preventing cervical, endometrial, and ovarian cancer. Experimental studies emphasize the chemopreventive and therapeutic potential of plant-derived substances by inhibiting the early stages of carcinogenesis or improving the efficacy of traditional chemotherapeutic agents. Moreover, a number of epidemiological studies have investigated associations between a plant-based diet and cancer risk. 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Krajewski, Rafał ; Makuch, Sebastian ; Agrawal, Siddarth</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c478t-b06fd8058bfe09072c41fe7ee57c2b78c481bc90d09dcae79281b2b93ad4282c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Acids</topic><topic>Animals</topic><topic>anticancer</topic><topic>Antitumor activity</topic><topic>Carcinogenesis</topic><topic>Carcinogens</topic><topic>Carotenoids</topic><topic>Cervical cancer</topic><topic>Cervix</topic><topic>Chemoprevention - methods</topic><topic>Chemotherapy</topic><topic>Diet</topic><topic>Disease prevention</topic><topic>Endometrial cancer</topic><topic>Endometrium</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Flavonoids</topic><topic>Fruits</topic><topic>Genital Neoplasms, Female - drug therapy</topic><topic>Genital Neoplasms, Female - prevention & control</topic><topic>Gynecological cancer</topic><topic>gynecological cancers</topic><topic>Gynecology</topic><topic>Human papillomavirus</topic><topic>Humans</topic><topic>Infections</topic><topic>Literature reviews</topic><topic>Medical screening</topic><topic>Ovarian cancer</topic><topic>Phytochemicals</topic><topic>Phytochemicals - chemistry</topic><topic>Phytochemicals - classification</topic><topic>Phytochemicals - pharmacology</topic><topic>Phytochemicals - therapeutic use</topic><topic>Plants</topic><topic>Polyphenols</topic><topic>Polyphenols - chemistry</topic><topic>Polyphenols - pharmacology</topic><topic>Polyphenols - therapeutic use</topic><topic>Review</topic><topic>Structure-Activity Relationship</topic><topic>Sulfhydryl Compounds - chemistry</topic><topic>Sulfhydryl Compounds - pharmacology</topic><topic>Sulfhydryl Compounds - therapeutic use</topic><topic>Terpenes - chemistry</topic><topic>Terpenes - pharmacology</topic><topic>Terpenes - therapeutic use</topic><topic>Tumors</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Woźniak, Marta</creatorcontrib><creatorcontrib>Krajewski, Rafał</creatorcontrib><creatorcontrib>Makuch, Sebastian</creatorcontrib><creatorcontrib>Agrawal, Siddarth</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest research library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>International journal of molecular sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Woźniak, Marta</au><au>Krajewski, Rafał</au><au>Makuch, Sebastian</au><au>Agrawal, Siddarth</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phytochemicals in Gynecological Cancer Prevention</atitle><jtitle>International journal of molecular sciences</jtitle><addtitle>Int J Mol Sci</addtitle><date>2021-01-26</date><risdate>2021</risdate><volume>22</volume><issue>3</issue><spage>1219</spage><pages>1219-</pages><issn>1422-0067</issn><issn>1661-6596</issn><eissn>1422-0067</eissn><abstract>Gynecological cancer confers an enormous burden among women worldwide. 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subjects | Acids Animals anticancer Antitumor activity Carcinogenesis Carcinogens Carotenoids Cervical cancer Cervix Chemoprevention - methods Chemotherapy Diet Disease prevention Endometrial cancer Endometrium Epidemiology Female Flavonoids Fruits Genital Neoplasms, Female - drug therapy Genital Neoplasms, Female - prevention & control Gynecological cancer gynecological cancers Gynecology Human papillomavirus Humans Infections Literature reviews Medical screening Ovarian cancer Phytochemicals Phytochemicals - chemistry Phytochemicals - classification Phytochemicals - pharmacology Phytochemicals - therapeutic use Plants Polyphenols Polyphenols - chemistry Polyphenols - pharmacology Polyphenols - therapeutic use Review Structure-Activity Relationship Sulfhydryl Compounds - chemistry Sulfhydryl Compounds - pharmacology Sulfhydryl Compounds - therapeutic use Terpenes - chemistry Terpenes - pharmacology Terpenes - therapeutic use Tumors Womens health |
title | Phytochemicals in Gynecological Cancer Prevention |
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